The science and questions surrounding chronic traumatic encephalopathy

Vin Shen Ban, Christopher J. Madden, Julian E. Bailes, H. Hunt Batjer, Russell R. Lonser

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Recently, the pathobiology, causes, associated factors, incidence and prevalence, and natural history of chronic traumatic encephalopathy (CTE) have been debated. Data from retrospective case series and high-profile media reports have fueled public fear and affected the medical community's understanding of the role of sports-related traumatic brain injury (TBI) in the development of CTE. There are a number of limitations posed by the current evidence that can lead to confusion within the public and scientific community. In this paper, the authors address common questions surrounding the science of CTE and propose future research directions.

Original languageEnglish (US)
Article numberE15
JournalNeurosurgical focus
Issue number4
StatePublished - Apr 1 2016


  • Chronic traumatic encephalopathy
  • Concussion
  • Controversies
  • Diagnosis
  • Research directions
  • Subconcussion
  • Treatment

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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