The sensory somatotopic map of the human hand demonstrated at 4 Tesla

Joseph A Maldjian, Allan Gottschalk, Rita S. Patel, John A. Detre, David C. Alsop

Research output: Contribution to journalArticle

130 Citations (Scopus)

Abstract

Recent attempts at high-resolution sensory-stimulated fMRI performed at 1.5 T have had very limited success at demonstrating a somatotopic organization for individual digits. Our purpose was to determine if functional MRI at 4 T can demonstrate the sensory somatotopic map of the human hand. Sensory functional MRI was performed at 4 T in five normal volunteers using a low-frequency vibratory stimulus on the pad of each finger of the left hand. A simple motor control task was also performed. The data were normalized to a standard atlas, and individual and group statistical parametric maps (SPMs) were computed for each task. Volume of activation and distribution of cluster maxima were compared for each task. For three of the subjects, the SPMs demonstrated a somatotopic organization of the sensory cortex. The group SPMs demonstrated a clear somatotopic organization of the sensory cortex. The thumb to fifth finger were organized, in general, with a lateral to medial, inferior to superior, and anterior to posterior relationship. There was overlap in the individual SPMs between fingers. The sensory activation spanned a space of 12-18 mm (thumb to fifth finger) on the primary sensory cortex. The motor activation occurred consistently at the superior-most extent of the sensory activation within and across subjects. The sensory somatotopic map of the human hand can be identified at 4 T. High- resolution imaging at 4 T can be useful for detailed functional imaging studies.

Original languageEnglish (US)
Pages (from-to)55-62
Number of pages8
JournalNeuroImage
Volume10
Issue number1
DOIs
StatePublished - Jan 1 1999

Fingerprint

Fingers
Hand
Thumb
Magnetic Resonance Imaging
Atlases
Healthy Volunteers

ASJC Scopus subject areas

  • Neurology
  • Cognitive Neuroscience

Cite this

The sensory somatotopic map of the human hand demonstrated at 4 Tesla. / Maldjian, Joseph A; Gottschalk, Allan; Patel, Rita S.; Detre, John A.; Alsop, David C.

In: NeuroImage, Vol. 10, No. 1, 01.01.1999, p. 55-62.

Research output: Contribution to journalArticle

Maldjian, JA, Gottschalk, A, Patel, RS, Detre, JA & Alsop, DC 1999, 'The sensory somatotopic map of the human hand demonstrated at 4 Tesla', NeuroImage, vol. 10, no. 1, pp. 55-62. https://doi.org/10.1006/nimg.1999.0448
Maldjian, Joseph A ; Gottschalk, Allan ; Patel, Rita S. ; Detre, John A. ; Alsop, David C. / The sensory somatotopic map of the human hand demonstrated at 4 Tesla. In: NeuroImage. 1999 ; Vol. 10, No. 1. pp. 55-62.
@article{6192317ff42f44dfbe5203112496aeaf,
title = "The sensory somatotopic map of the human hand demonstrated at 4 Tesla",
abstract = "Recent attempts at high-resolution sensory-stimulated fMRI performed at 1.5 T have had very limited success at demonstrating a somatotopic organization for individual digits. Our purpose was to determine if functional MRI at 4 T can demonstrate the sensory somatotopic map of the human hand. Sensory functional MRI was performed at 4 T in five normal volunteers using a low-frequency vibratory stimulus on the pad of each finger of the left hand. A simple motor control task was also performed. The data were normalized to a standard atlas, and individual and group statistical parametric maps (SPMs) were computed for each task. Volume of activation and distribution of cluster maxima were compared for each task. For three of the subjects, the SPMs demonstrated a somatotopic organization of the sensory cortex. The group SPMs demonstrated a clear somatotopic organization of the sensory cortex. The thumb to fifth finger were organized, in general, with a lateral to medial, inferior to superior, and anterior to posterior relationship. There was overlap in the individual SPMs between fingers. The sensory activation spanned a space of 12-18 mm (thumb to fifth finger) on the primary sensory cortex. The motor activation occurred consistently at the superior-most extent of the sensory activation within and across subjects. The sensory somatotopic map of the human hand can be identified at 4 T. High- resolution imaging at 4 T can be useful for detailed functional imaging studies.",
author = "Maldjian, {Joseph A} and Allan Gottschalk and Patel, {Rita S.} and Detre, {John A.} and Alsop, {David C.}",
year = "1999",
month = "1",
day = "1",
doi = "10.1006/nimg.1999.0448",
language = "English (US)",
volume = "10",
pages = "55--62",
journal = "NeuroImage",
issn = "1053-8119",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - The sensory somatotopic map of the human hand demonstrated at 4 Tesla

AU - Maldjian, Joseph A

AU - Gottschalk, Allan

AU - Patel, Rita S.

AU - Detre, John A.

AU - Alsop, David C.

PY - 1999/1/1

Y1 - 1999/1/1

N2 - Recent attempts at high-resolution sensory-stimulated fMRI performed at 1.5 T have had very limited success at demonstrating a somatotopic organization for individual digits. Our purpose was to determine if functional MRI at 4 T can demonstrate the sensory somatotopic map of the human hand. Sensory functional MRI was performed at 4 T in five normal volunteers using a low-frequency vibratory stimulus on the pad of each finger of the left hand. A simple motor control task was also performed. The data were normalized to a standard atlas, and individual and group statistical parametric maps (SPMs) were computed for each task. Volume of activation and distribution of cluster maxima were compared for each task. For three of the subjects, the SPMs demonstrated a somatotopic organization of the sensory cortex. The group SPMs demonstrated a clear somatotopic organization of the sensory cortex. The thumb to fifth finger were organized, in general, with a lateral to medial, inferior to superior, and anterior to posterior relationship. There was overlap in the individual SPMs between fingers. The sensory activation spanned a space of 12-18 mm (thumb to fifth finger) on the primary sensory cortex. The motor activation occurred consistently at the superior-most extent of the sensory activation within and across subjects. The sensory somatotopic map of the human hand can be identified at 4 T. High- resolution imaging at 4 T can be useful for detailed functional imaging studies.

AB - Recent attempts at high-resolution sensory-stimulated fMRI performed at 1.5 T have had very limited success at demonstrating a somatotopic organization for individual digits. Our purpose was to determine if functional MRI at 4 T can demonstrate the sensory somatotopic map of the human hand. Sensory functional MRI was performed at 4 T in five normal volunteers using a low-frequency vibratory stimulus on the pad of each finger of the left hand. A simple motor control task was also performed. The data were normalized to a standard atlas, and individual and group statistical parametric maps (SPMs) were computed for each task. Volume of activation and distribution of cluster maxima were compared for each task. For three of the subjects, the SPMs demonstrated a somatotopic organization of the sensory cortex. The group SPMs demonstrated a clear somatotopic organization of the sensory cortex. The thumb to fifth finger were organized, in general, with a lateral to medial, inferior to superior, and anterior to posterior relationship. There was overlap in the individual SPMs between fingers. The sensory activation spanned a space of 12-18 mm (thumb to fifth finger) on the primary sensory cortex. The motor activation occurred consistently at the superior-most extent of the sensory activation within and across subjects. The sensory somatotopic map of the human hand can be identified at 4 T. High- resolution imaging at 4 T can be useful for detailed functional imaging studies.

UR - http://www.scopus.com/inward/record.url?scp=0032790895&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032790895&partnerID=8YFLogxK

U2 - 10.1006/nimg.1999.0448

DO - 10.1006/nimg.1999.0448

M3 - Article

C2 - 10385581

AN - SCOPUS:0032790895

VL - 10

SP - 55

EP - 62

JO - NeuroImage

JF - NeuroImage

SN - 1053-8119

IS - 1

ER -