The septum pellucidum: Normal and abnormal

Research output: Contribution to journalArticle

140 Citations (Scopus)

Abstract

The common embryologic origin of the septum pellucidum, of the corpus callosum, and of the limbic system explains the anatomic basis of a varying degree of concurrent involvement of these structures in disease processes, both developmental and acquired. Developmental absence of the septum pellucidum portends a more generalized dysplasia that encompasses the corpus callosum and the limbic system. When considered in this context, it is easy to understand the limbic system dysfunction that is engendered by this anomaly. It is rare for an acquired lesion to involve the septum pellucidum per se because of its small size. However, it is common for it to be secondarily involved in almost all types of acquired disease processes. With the exquisite anatomic morphology that MR now provides, one must carefully assess involvement of the septum pellucidum, of the corpus callosum, and of the limbic system in disease processes that occur in the vicinity of these structures, so that more incisive clinical insight into the functions that are subserved by these structures can be obtained.

Original languageEnglish (US)
Pages (from-to)989-1005
Number of pages17
JournalAmerican Journal of Neuroradiology
Volume10
Issue number5
StatePublished - 1989

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Septum Pellucidum
Limbic System
Corpus Callosum

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

The septum pellucidum : Normal and abnormal. / Sarwar, M.

In: American Journal of Neuroradiology, Vol. 10, No. 5, 1989, p. 989-1005.

Research output: Contribution to journalArticle

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