The tissue distribution of fructose-2,6-P2 and fructose-6-P,2-kinase in rats and the effect of starvation diabetes and hypoglycemia on hepatic fructose-2,6-P2 and fructose-6-P,2-kinase

Masamichi Kuwajima, Kosaku Uyeda

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

The tissue distribution of fructose-2,6-P2 and fructose-6-P,2-kinase in rats was determined. The highest concentration of fructose-2,6-P2 was found in liver, followed by brain, heart muscle, kidney, testis and skeletal muscle in decreasing order. Similar results were obtained with fructose-6-P,2-kinase activities in these tissues. Starvation, streptozotocin-induced diabetes or hypoglycemia lowers the fructose-2,6-P2 levels and fructose-6-P,2-kinase activity in the liver.

Original languageEnglish (US)
Pages (from-to)84-88
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume104
Issue number1
DOIs
StatePublished - Jan 15 1982

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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