The treatment of systemic lupus proliferative nephritis

Marilynn G. Punaro

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE) in childhood affecting more than 80 % of patients. Treatment of this complication has undergone significant evolution in recent years. A series of randomized controlled trials has clarified the role of a variety of immunomodulating regimens including some novel biologic medications. This review touches on the major trials that have influenced practice and shaped current thinking about the treatment of proliferative lupus glomerulonephritis.

Original languageEnglish (US)
Pages (from-to)2069-2078
Number of pages10
JournalPediatric Nephrology
Volume28
Issue number11
DOIs
StatePublished - Nov 1 2013

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Keywords

  • Lupus
  • Mycophenolate mofetil
  • Nephritis
  • Pediatric lupus
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

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