The tumor necrosis factors

Cachectin and lymphotoxin

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The extensive tissue damage associated with endotoxemia and the phenomenon of tumor necrosis are both triggered by cachectin and lymphotoxin - two leukocyte products with potentially toxic effects on virtually every organ system. Understanding the role of these cytokines in the pathogenesis of inflammation may lead to effective therapy for a wide range of diseases.

Original languageEnglish (US)
Pages (from-to)45-56
Number of pages12
JournalHospital Practice
Volume25
Issue number2
StatePublished - 1990

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Lymphotoxin-alpha
Endotoxemia
Poisons
Leukocytes
Necrosis
Tumor Necrosis Factor-alpha
Cytokines
Inflammation
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The tumor necrosis factors : Cachectin and lymphotoxin. / Beutler, B.

In: Hospital Practice, Vol. 25, No. 2, 1990, p. 45-56.

Research output: Contribution to journalArticle

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