The extensive tissue damage associated with endotoxemia and the phenomenon of tumor necrosis are both triggered by cachectin and lymphotoxin - two leukocyte products with potentially toxic effects on virtually every organ system. Understanding the role of these cytokines in the pathogenesis of inflammation may lead to effective therapy for a wide range of diseases.
|Original language||English (US)|
|Number of pages||12|
|State||Published - Jan 1 1990|
ASJC Scopus subject areas