The use of cellular reagents as an adjunct to typing for HLA-DRw10

E. J. Ball, P. Stastny

Research output: Contribution to journalArticle

Abstract

Two human T cell lines recognizing DRw10 were generated. One line was directly alloreactive, while a second cloned line recognized mumps virus in the context of a DRw10-like determinant. In panel studies, the lines responded only to DRw10 cells, and not to DR1 (DRw10-) cells. When compared to 5 anti-DRw10 sera, the cellular reagents gave virtually identical results. The generation and use of such cellular reagents may be of particular value for the identification of HLA-D-region specificities that are rare, poorly defined, or for which serologic typing reagents are limited.

Original languageEnglish (US)
Pages (from-to)155-159
Number of pages5
JournalTissue Antigens
Volume24
Issue number3
StatePublished - 1984

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Mumps virus
HLA-D Antigens
T-Lymphocytes
Cell Line
Serum
HLA-DRw10

ASJC Scopus subject areas

  • Cell Biology
  • Immunology

Cite this

Ball, E. J., & Stastny, P. (1984). The use of cellular reagents as an adjunct to typing for HLA-DRw10. Tissue Antigens, 24(3), 155-159.

The use of cellular reagents as an adjunct to typing for HLA-DRw10. / Ball, E. J.; Stastny, P.

In: Tissue Antigens, Vol. 24, No. 3, 1984, p. 155-159.

Research output: Contribution to journalArticle

Ball, EJ & Stastny, P 1984, 'The use of cellular reagents as an adjunct to typing for HLA-DRw10', Tissue Antigens, vol. 24, no. 3, pp. 155-159.
Ball, E. J. ; Stastny, P. / The use of cellular reagents as an adjunct to typing for HLA-DRw10. In: Tissue Antigens. 1984 ; Vol. 24, No. 3. pp. 155-159.
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