Abstract
The formula GFR = kL/Pcr can be used to estimate GFR in infants, children, and adolescents who have grossly normal body habitus and are in steady-state condition. GFR is expressed in ml/min per 1.73m2 BSA, L represents body length in cm. Pcr represents plasma creatinine concentration in mg per dl and k is a constant of proportionality that reflects the relationship between urinary creatinine excretion and units of body size. The value of k varies as a function of age and sex being 0.33 in preterm infants, 0.45 in full-term infants, 0.55 in children and adolescent girls, and 0.70 in adolescent boys. The advantages of rapid determination, reasonable accuracy, and the avoidance of urine collection justify the use of this formula in pediatric patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 571-590 |
| Number of pages | 20 |
| Journal | Pediatric Clinics of North America |
| Volume | 34 |
| Issue number | 3 |
| State | Published - 1987 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
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The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. / Schwartz, G. J.; Brion, L. P.; Spitzer, A.
In: Pediatric Clinics of North America, Vol. 34, No. 3, 1987, p. 571-590.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents
AU - Schwartz, G. J.
AU - Brion, L. P.
AU - Spitzer, A.
PY - 1987
Y1 - 1987
N2 - The formula GFR = kL/Pcr can be used to estimate GFR in infants, children, and adolescents who have grossly normal body habitus and are in steady-state condition. GFR is expressed in ml/min per 1.73m2 BSA, L represents body length in cm. Pcr represents plasma creatinine concentration in mg per dl and k is a constant of proportionality that reflects the relationship between urinary creatinine excretion and units of body size. The value of k varies as a function of age and sex being 0.33 in preterm infants, 0.45 in full-term infants, 0.55 in children and adolescent girls, and 0.70 in adolescent boys. The advantages of rapid determination, reasonable accuracy, and the avoidance of urine collection justify the use of this formula in pediatric patients.
AB - The formula GFR = kL/Pcr can be used to estimate GFR in infants, children, and adolescents who have grossly normal body habitus and are in steady-state condition. GFR is expressed in ml/min per 1.73m2 BSA, L represents body length in cm. Pcr represents plasma creatinine concentration in mg per dl and k is a constant of proportionality that reflects the relationship between urinary creatinine excretion and units of body size. The value of k varies as a function of age and sex being 0.33 in preterm infants, 0.45 in full-term infants, 0.55 in children and adolescent girls, and 0.70 in adolescent boys. The advantages of rapid determination, reasonable accuracy, and the avoidance of urine collection justify the use of this formula in pediatric patients.
UR - http://www.scopus.com/inward/record.url?scp=0023179130&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023179130&partnerID=8YFLogxK
M3 - Article
VL - 34
SP - 571
EP - 590
JO - Pediatric Clinics of North America
JF - Pediatric Clinics of North America
SN - 0031-3955
IS - 3
ER -