The value of surveillance testing in childhood brain tumors

Lawrence E. Kun; Bernard D'Souza; Melvin Tefft

doi:10.1002/1097-0142(19851001)56:7+<1818::AID-CNCR2820561320>3.0.CO;2-9

The value of surveillance testing in childhood brain tumors

Lawrence E. Kun, Bernard D'Souza, Melvin Tefft

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Follow‐up procedures in children with brain tumors are designed to confirm tumor response to initial therapy, identify recurrence or progression at the time of potential secondary treatment, and establish the patterns of failure. Serial use of neurologic examinations and computerized tomography scans are outlined for all tumor types. Tumors capable of subarachnoid metastasis (medulloblastoma, ependymomas, pineal/suprasellar germ cell tumors, and pineoblastoma) require periodic assessment of the neuraxis by cerebrospinal fluid (CSF) cytology and myelography to establish the frequency of subclinical meningeal seeding in study settings. Serial analysis of specific biochemical markers for medulloblastoma (CSF polyamines) and germ cell tumors (serum and CSF alpha‐fetoprotein and β‐human chorionic gonadotropin) are suggested. Serial evoked potentials in brain stem gliomas are recommended. Cancer 56: 1818‐1823, 1985.

Original language	English (US)
Pages (from-to)	1818-1823
Number of pages	6
Journal	Cancer
Volume	56
Issue number	7 S
DOIs	https://doi.org/10.1002/1097-0142(19851001)56:7+<1818::AID-CNCR2820561320>3.0.CO;2-9
State	Published - Oct 1 1985

ASJC Scopus subject areas

Oncology
Cancer Research

Access to Document

10.1002/1097-0142(19851001)56:7+<1818::AID-CNCR2820561320>3.0.CO;2-9

Cite this

@article{411d1dd812da4bfebe9cc64c2374c4e5,

title = "The value of surveillance testing in childhood brain tumors",

abstract = "Follow‐up procedures in children with brain tumors are designed to confirm tumor response to initial therapy, identify recurrence or progression at the time of potential secondary treatment, and establish the patterns of failure. Serial use of neurologic examinations and computerized tomography scans are outlined for all tumor types. Tumors capable of subarachnoid metastasis (medulloblastoma, ependymomas, pineal/suprasellar germ cell tumors, and pineoblastoma) require periodic assessment of the neuraxis by cerebrospinal fluid (CSF) cytology and myelography to establish the frequency of subclinical meningeal seeding in study settings. Serial analysis of specific biochemical markers for medulloblastoma (CSF polyamines) and germ cell tumors (serum and CSF alpha‐fetoprotein and β‐human chorionic gonadotropin) are suggested. Serial evoked potentials in brain stem gliomas are recommended. Cancer 56: 1818‐1823, 1985.",

author = "Kun, {Lawrence E.} and Bernard D'Souza and Melvin Tefft",

year = "1985",

month = oct,

day = "1",

doi = "10.1002/1097-0142(19851001)56:7+<1818::AID-CNCR2820561320>3.0.CO;2-9",

language = "English (US)",

volume = "56",

pages = "1818--1823",

journal = "Cancer",

issn = "0008-543X",

publisher = "John Wiley and Sons Inc.",

number = "7 S",

}

TY - JOUR

T1 - The value of surveillance testing in childhood brain tumors

AU - Kun, Lawrence E.

AU - D'Souza, Bernard

AU - Tefft, Melvin

PY - 1985/10/1

Y1 - 1985/10/1

N2 - Follow‐up procedures in children with brain tumors are designed to confirm tumor response to initial therapy, identify recurrence or progression at the time of potential secondary treatment, and establish the patterns of failure. Serial use of neurologic examinations and computerized tomography scans are outlined for all tumor types. Tumors capable of subarachnoid metastasis (medulloblastoma, ependymomas, pineal/suprasellar germ cell tumors, and pineoblastoma) require periodic assessment of the neuraxis by cerebrospinal fluid (CSF) cytology and myelography to establish the frequency of subclinical meningeal seeding in study settings. Serial analysis of specific biochemical markers for medulloblastoma (CSF polyamines) and germ cell tumors (serum and CSF alpha‐fetoprotein and β‐human chorionic gonadotropin) are suggested. Serial evoked potentials in brain stem gliomas are recommended. Cancer 56: 1818‐1823, 1985.

AB - Follow‐up procedures in children with brain tumors are designed to confirm tumor response to initial therapy, identify recurrence or progression at the time of potential secondary treatment, and establish the patterns of failure. Serial use of neurologic examinations and computerized tomography scans are outlined for all tumor types. Tumors capable of subarachnoid metastasis (medulloblastoma, ependymomas, pineal/suprasellar germ cell tumors, and pineoblastoma) require periodic assessment of the neuraxis by cerebrospinal fluid (CSF) cytology and myelography to establish the frequency of subclinical meningeal seeding in study settings. Serial analysis of specific biochemical markers for medulloblastoma (CSF polyamines) and germ cell tumors (serum and CSF alpha‐fetoprotein and β‐human chorionic gonadotropin) are suggested. Serial evoked potentials in brain stem gliomas are recommended. Cancer 56: 1818‐1823, 1985.

UR - http://www.scopus.com/inward/record.url?scp=0022346904&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022346904&partnerID=8YFLogxK

U2 - 10.1002/1097-0142(19851001)56:7+<1818::AID-CNCR2820561320>3.0.CO;2-9

DO - 10.1002/1097-0142(19851001)56:7+<1818::AID-CNCR2820561320>3.0.CO;2-9

M3 - Article

C2 - 4027919

AN - SCOPUS:0022346904

SN - 0008-543X

VL - 56

SP - 1818

EP - 1823

JO - Cancer

JF - Cancer

IS - 7 S

ER -

The value of surveillance testing in childhood brain tumors

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this