The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry

Samuel Han; Jennifer M. Kolb; Patrick Hosokawa; Chloe Friedman; Charlie Fox; Frank I. Scott; Christopher H. Lieu; Ravy K. Vajravelu; Martin McCarter; Caitlin C. Murphy; Michael B. Cook; Ana Gleisner; Gary W. Falk; David A. Katzka; Sachin Wani

doi:10.14309/ajg.0000000000001046

The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry

Samuel Han, Jennifer M. Kolb, Patrick Hosokawa, Chloe Friedman, Charlie Fox, Frank I. Scott, Christopher H. Lieu, Ravy K. Vajravelu, Martin McCarter, Caitlin C. Murphy, Michael B. Cook, Ana Gleisner, Gary W. Falk, David A. Katzka, Sachin Wani

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

INTRODUCTION:Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.METHODS:We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.RESULTS:In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).DISCUSSION:This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

Original language	English (US)
Pages (from-to)	811-815
Number of pages	5
Journal	American Journal of Gastroenterology
Volume	116
Issue number	4
DOIs	https://doi.org/10.14309/ajg.0000000000001046
State	Published - Apr 1 2021

ASJC Scopus subject areas

Hepatology
Gastroenterology

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Han, S., Kolb, J. M., Hosokawa, P., Friedman, C., Fox, C., Scott, F. I., Lieu, C. H., Vajravelu, R. K., McCarter, M., Murphy, C. C., Cook, M. B., Gleisner, A., Falk, G. W., Katzka, D. A., & Wani, S. (2021). The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry. American Journal of Gastroenterology, 116(4), 811-815. https://doi.org/10.14309/ajg.0000000000001046

Han, S, Kolb, JM, Hosokawa, P, Friedman, C, Fox, C, Scott, FI, Lieu, CH, Vajravelu, RK, McCarter, M, Murphy, CC, Cook, MB, Gleisner, A, Falk, GW, Katzka, DA & Wani, S 2021, 'The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry', American Journal of Gastroenterology, vol. 116, no. 4, pp. 811-815. https://doi.org/10.14309/ajg.0000000000001046

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abstract = "INTRODUCTION:Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.METHODS:We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.RESULTS:In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).DISCUSSION:This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.",

author = "Samuel Han and Kolb, {Jennifer M.} and Patrick Hosokawa and Chloe Friedman and Charlie Fox and Scott, {Frank I.} and Lieu, {Christopher H.} and Vajravelu, {Ravy K.} and Martin McCarter and Murphy, {Caitlin C.} and Cook, {Michael B.} and Ana Gleisner and Falk, {Gary W.} and Katzka, {David A.} and Sachin Wani",

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T1 - The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma

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AU - Han, Samuel

AU - Kolb, Jennifer M.

AU - Hosokawa, Patrick

AU - Friedman, Chloe

AU - Fox, Charlie

AU - Scott, Frank I.

AU - Lieu, Christopher H.

AU - Vajravelu, Ravy K.

AU - McCarter, Martin

AU - Murphy, Caitlin C.

AU - Cook, Michael B.

AU - Gleisner, Ana

AU - Falk, Gary W.

AU - Katzka, David A.

AU - Wani, Sachin

PY - 2021/4/1

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N2 - INTRODUCTION:Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.METHODS:We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.RESULTS:In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).DISCUSSION:This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

AB - INTRODUCTION:Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival.METHODS:We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival.RESULTS:In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1-4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70-0.91).DISCUSSION:This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.

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The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry

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