The Washington Heights-Inwood Genetic Study of Essential Tremor: Methodologic Issues in Essential-Tremor Research

Elan D. Louis, Ruth Ottman, Blair Ford, Seth Pullman, Moises Martinez, Stanley Fahrt, W. Allen Hauser

Research output: Contribution to journalArticle

175 Scopus citations

Abstract

Essential tremor (ET) is the most prevalent movement disorder. It is unknown to what extent ET clusters within families, and the role of genetic susceptibility in the etiology of ET has not been adequately investigated at the population level. The problem is largely methodological, with few well-designed studies. The Washington Heights-lnwood Genetic Study of ET, begun in 1995, is designed to investigate the genetics of ET using a methodology that has not been applied to ET research to date. Part of the design includes a new set of clinical and electrophysiological diagnostic criteria for ET; the present paper describes this novel study design.

Original languageEnglish (US)
Pages (from-to)124-133
Number of pages10
JournalNeuroepidemiology
Volume16
Issue number3
DOIs
StatePublished - Jan 1 1997
Externally publishedYes

Keywords

  • Epidemiology
  • Essential tremor
  • Family history
  • Genetics
  • Methodology

ASJC Scopus subject areas

  • Epidemiology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'The Washington Heights-Inwood Genetic Study of Essential Tremor: Methodologic Issues in Essential-Tremor Research'. Together they form a unique fingerprint.

  • Cite this