The Washington Heights-Inwood Genetic Study of Essential Tremor: Methodologic Issues in Essential-Tremor Research

Elan D. Louis; Ruth Ottman; Blair Ford; Seth Pullman; Moises Martinez; Stanley Fahrt; W. Allen Hauser

doi:10.1159/000109681

The Washington Heights-Inwood Genetic Study of Essential Tremor: Methodologic Issues in Essential-Tremor Research

Elan D. Louis, Ruth Ottman, Blair Ford, Seth Pullman, Moises Martinez, Stanley Fahrt, W. Allen Hauser

Research output: Contribution to journal › Article › peer-review

241 Scopus citations

Abstract

Essential tremor (ET) is the most prevalent movement disorder. It is unknown to what extent ET clusters within families, and the role of genetic susceptibility in the etiology of ET has not been adequately investigated at the population level. The problem is largely methodological, with few well-designed studies. The Washington Heights-lnwood Genetic Study of ET, begun in 1995, is designed to investigate the genetics of ET using a methodology that has not been applied to ET research to date. Part of the design includes a new set of clinical and electrophysiological diagnostic criteria for ET; the present paper describes this novel study design.

Original language	English (US)
Pages (from-to)	124-133
Number of pages	10
Journal	Neuroepidemiology
Volume	16
Issue number	3
DOIs	https://doi.org/10.1159/000109681
State	Published - 1997
Externally published	Yes

Keywords

Epidemiology
Essential tremor
Family history
Genetics
Methodology

ASJC Scopus subject areas

Epidemiology
Clinical Neurology

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10.1159/000109681

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title = "The Washington Heights-Inwood Genetic Study of Essential Tremor: Methodologic Issues in Essential-Tremor Research",

abstract = "Essential tremor (ET) is the most prevalent movement disorder. It is unknown to what extent ET clusters within families, and the role of genetic susceptibility in the etiology of ET has not been adequately investigated at the population level. The problem is largely methodological, with few well-designed studies. The Washington Heights-lnwood Genetic Study of ET, begun in 1995, is designed to investigate the genetics of ET using a methodology that has not been applied to ET research to date. Part of the design includes a new set of clinical and electrophysiological diagnostic criteria for ET; the present paper describes this novel study design.",

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AU - Pullman, Seth

AU - Martinez, Moises

AU - Fahrt, Stanley

AU - Hauser, W. Allen

PY - 1997

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N2 - Essential tremor (ET) is the most prevalent movement disorder. It is unknown to what extent ET clusters within families, and the role of genetic susceptibility in the etiology of ET has not been adequately investigated at the population level. The problem is largely methodological, with few well-designed studies. The Washington Heights-lnwood Genetic Study of ET, begun in 1995, is designed to investigate the genetics of ET using a methodology that has not been applied to ET research to date. Part of the design includes a new set of clinical and electrophysiological diagnostic criteria for ET; the present paper describes this novel study design.

AB - Essential tremor (ET) is the most prevalent movement disorder. It is unknown to what extent ET clusters within families, and the role of genetic susceptibility in the etiology of ET has not been adequately investigated at the population level. The problem is largely methodological, with few well-designed studies. The Washington Heights-lnwood Genetic Study of ET, begun in 1995, is designed to investigate the genetics of ET using a methodology that has not been applied to ET research to date. Part of the design includes a new set of clinical and electrophysiological diagnostic criteria for ET; the present paper describes this novel study design.

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KW - Family history

KW - Genetics

KW - Methodology

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The Washington Heights-Inwood Genetic Study of Essential Tremor: Methodologic Issues in Essential-Tremor Research

Abstract

Keywords

ASJC Scopus subject areas

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