Thematic series on the pathobiology of vascular calcification: An introduction

Dwight A. Towler, Linda L. Demer

Research output: Contribution to journalReview article

34 Scopus citations

Abstract

Vascular calcification increasingly afflicts our aging, dysmetabolic population. Once considered only a passive process of dead and dying cells, data from multiple laboratories worldwide have converged to demonstrate that vascular calcification is a highly regulated form of biomineralization. The goal of this thematic review series is to highlight what is known concerning the biological "players" and "game rules" with respect to vascular mineral metabolism. Armed with this understanding, it is hoped that novel therapeutic strategies can be crafted to prevent and treat vascular calcium accrual, to the benefit of our patients afflicted with arteriosclerotic valvular and vascular diseases.

Original languageEnglish (US)
Pages (from-to)1378-1380
Number of pages3
JournalCirculation research
Volume108
Issue number11
DOIs
StatePublished - May 27 2011

    Fingerprint

Keywords

  • arteriosclerosis
  • atherosclerosis
  • calcific aortic stenosis
  • review
  • vascular calcification

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this