Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits

Subhendra N. Sarkar, Efstathios Papavassiliou, David B. Hackney, David C. Alsop, Ludy C. Shih, Ananth J. Madhuranthakam, Reed F. Busse, Susan La Ruche, Rafeeque A. Bhadelia

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: For patients with deep brain stimulators (DBS), local absorbed radiofrequency (RF) power is unknown and is much higher than what the system estimates. We developed a comprehensive, high-quality brain magnetic resonance imaging (MRI) protocol for DBS patients utilizing three-dimensional (3D) magnetic resonance sequences at very low RF power. Methods: Six patients with DBS were imaged (10 sessions) using a transmit/receive head coil at 1.5 Tesla with modified 3D sequences within ultra-low specific absorption rate (SAR) limits (0.1 W/kg) using T2, fast fluid-attenuated inversion recovery (FLAIR) and T1-weighted image contrast. Tissue signal and tissue contrast from the low-SAR images were subjectively and objectively compared with routine clinical images of six age-matched controls. Results: Low-SAR images of DBS patients demonstrated tissue contrast comparable to high-SAR images and were of diagnostic quality except for slightly reduced signal. Conclusions: Although preliminary, we demonstrated diagnostic quality brain MRI with optimized, volumetric sequences in DBS patients within very conservative RF safety guidelines offering a greater safety margin.

Original languageEnglish (US)
Pages (from-to)546-549
Number of pages4
JournalMovement Disorders
Volume29
Issue number4
DOIs
StatePublished - 2014

Fingerprint

Magnetic Resonance Imaging
Brain
Safety
Magnetic Resonance Spectroscopy
Head
Guidelines

Keywords

  • Conditional magnetic resonance imaging
  • Deep brain stimulation
  • Low specific absorption rate
  • Parkinson's disease
  • Radiofrequency heating

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Sarkar, S. N., Papavassiliou, E., Hackney, D. B., Alsop, D. C., Shih, L. C., Madhuranthakam, A. J., ... Bhadelia, R. A. (2014). Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits. Movement Disorders, 29(4), 546-549. https://doi.org/10.1002/mds.25808

Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits. / Sarkar, Subhendra N.; Papavassiliou, Efstathios; Hackney, David B.; Alsop, David C.; Shih, Ludy C.; Madhuranthakam, Ananth J.; Busse, Reed F.; La Ruche, Susan; Bhadelia, Rafeeque A.

In: Movement Disorders, Vol. 29, No. 4, 2014, p. 546-549.

Research output: Contribution to journalArticle

Sarkar, SN, Papavassiliou, E, Hackney, DB, Alsop, DC, Shih, LC, Madhuranthakam, AJ, Busse, RF, La Ruche, S & Bhadelia, RA 2014, 'Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits', Movement Disorders, vol. 29, no. 4, pp. 546-549. https://doi.org/10.1002/mds.25808
Sarkar, Subhendra N. ; Papavassiliou, Efstathios ; Hackney, David B. ; Alsop, David C. ; Shih, Ludy C. ; Madhuranthakam, Ananth J. ; Busse, Reed F. ; La Ruche, Susan ; Bhadelia, Rafeeque A. / Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits. In: Movement Disorders. 2014 ; Vol. 29, No. 4. pp. 546-549.
@article{fcfea7b31b124a1b96ad00c70fe9efcf,
title = "Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits",
abstract = "Background: For patients with deep brain stimulators (DBS), local absorbed radiofrequency (RF) power is unknown and is much higher than what the system estimates. We developed a comprehensive, high-quality brain magnetic resonance imaging (MRI) protocol for DBS patients utilizing three-dimensional (3D) magnetic resonance sequences at very low RF power. Methods: Six patients with DBS were imaged (10 sessions) using a transmit/receive head coil at 1.5 Tesla with modified 3D sequences within ultra-low specific absorption rate (SAR) limits (0.1 W/kg) using T2, fast fluid-attenuated inversion recovery (FLAIR) and T1-weighted image contrast. Tissue signal and tissue contrast from the low-SAR images were subjectively and objectively compared with routine clinical images of six age-matched controls. Results: Low-SAR images of DBS patients demonstrated tissue contrast comparable to high-SAR images and were of diagnostic quality except for slightly reduced signal. Conclusions: Although preliminary, we demonstrated diagnostic quality brain MRI with optimized, volumetric sequences in DBS patients within very conservative RF safety guidelines offering a greater safety margin.",
keywords = "Conditional magnetic resonance imaging, Deep brain stimulation, Low specific absorption rate, Parkinson's disease, Radiofrequency heating",
author = "Sarkar, {Subhendra N.} and Efstathios Papavassiliou and Hackney, {David B.} and Alsop, {David C.} and Shih, {Ludy C.} and Madhuranthakam, {Ananth J.} and Busse, {Reed F.} and {La Ruche}, Susan and Bhadelia, {Rafeeque A.}",
year = "2014",
doi = "10.1002/mds.25808",
language = "English (US)",
volume = "29",
pages = "546--549",
journal = "Movement Disorders",
issn = "0885-3185",
publisher = "John Wiley and Sons Inc.",
number = "4",

}

TY - JOUR

T1 - Three-dimensional brain MRI for DBS patients within ultra-low radiofrequency power limits

AU - Sarkar, Subhendra N.

AU - Papavassiliou, Efstathios

AU - Hackney, David B.

AU - Alsop, David C.

AU - Shih, Ludy C.

AU - Madhuranthakam, Ananth J.

AU - Busse, Reed F.

AU - La Ruche, Susan

AU - Bhadelia, Rafeeque A.

PY - 2014

Y1 - 2014

N2 - Background: For patients with deep brain stimulators (DBS), local absorbed radiofrequency (RF) power is unknown and is much higher than what the system estimates. We developed a comprehensive, high-quality brain magnetic resonance imaging (MRI) protocol for DBS patients utilizing three-dimensional (3D) magnetic resonance sequences at very low RF power. Methods: Six patients with DBS were imaged (10 sessions) using a transmit/receive head coil at 1.5 Tesla with modified 3D sequences within ultra-low specific absorption rate (SAR) limits (0.1 W/kg) using T2, fast fluid-attenuated inversion recovery (FLAIR) and T1-weighted image contrast. Tissue signal and tissue contrast from the low-SAR images were subjectively and objectively compared with routine clinical images of six age-matched controls. Results: Low-SAR images of DBS patients demonstrated tissue contrast comparable to high-SAR images and were of diagnostic quality except for slightly reduced signal. Conclusions: Although preliminary, we demonstrated diagnostic quality brain MRI with optimized, volumetric sequences in DBS patients within very conservative RF safety guidelines offering a greater safety margin.

AB - Background: For patients with deep brain stimulators (DBS), local absorbed radiofrequency (RF) power is unknown and is much higher than what the system estimates. We developed a comprehensive, high-quality brain magnetic resonance imaging (MRI) protocol for DBS patients utilizing three-dimensional (3D) magnetic resonance sequences at very low RF power. Methods: Six patients with DBS were imaged (10 sessions) using a transmit/receive head coil at 1.5 Tesla with modified 3D sequences within ultra-low specific absorption rate (SAR) limits (0.1 W/kg) using T2, fast fluid-attenuated inversion recovery (FLAIR) and T1-weighted image contrast. Tissue signal and tissue contrast from the low-SAR images were subjectively and objectively compared with routine clinical images of six age-matched controls. Results: Low-SAR images of DBS patients demonstrated tissue contrast comparable to high-SAR images and were of diagnostic quality except for slightly reduced signal. Conclusions: Although preliminary, we demonstrated diagnostic quality brain MRI with optimized, volumetric sequences in DBS patients within very conservative RF safety guidelines offering a greater safety margin.

KW - Conditional magnetic resonance imaging

KW - Deep brain stimulation

KW - Low specific absorption rate

KW - Parkinson's disease

KW - Radiofrequency heating

UR - http://www.scopus.com/inward/record.url?scp=84898058567&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84898058567&partnerID=8YFLogxK

U2 - 10.1002/mds.25808

DO - 10.1002/mds.25808

M3 - Article

VL - 29

SP - 546

EP - 549

JO - Movement Disorders

JF - Movement Disorders

SN - 0885-3185

IS - 4

ER -