Three patients with full facial transplantation

Bohdan Pomahac; Julian Pribaz; Elof Eriksson; Ericka M. Bueno; J. Rodrigo Diaz-Siso; Frank J. Rybicki; Donald J. Annino; Dennis Orgill; Edward J. Caterson; Stephanie A. Caterson; Matthew J. Carty; Yoon S. Chun; Christian E. Sampson; Jeffrey E. Janis; Daniel S. Alam; Arturo Saavedra; Joseph A. Molnar; Thomas Edrich; Francisco M. Marty; Stefan G. Tullius

doi:10.1056/NEJMoa1111432

Three patients with full facial transplantation

Bohdan Pomahac, Julian Pribaz, Elof Eriksson, Ericka M. Bueno, J. Rodrigo Diaz-Siso, Frank J. Rybicki, Donald J. Annino, Dennis Orgill, Edward J. Caterson, Stephanie A. Caterson, Matthew J. Carty, Yoon S. Chun, Christian E. Sampson, Jeffrey E. Janis, Daniel S. Alam, Arturo Saavedra, Joseph A. Molnar, Thomas Edrich, Francisco M. Marty, Stefan G. Tullius

Plastic Surgery

Research output: Contribution to journal › Article › peer-review

206 Scopus citations

Abstract

Unlike conventional reconstruction, facial transplantation seeks to correct severe deformities in a single operation. We report on three patients who received full-face transplants at our institution in 2011 in operations that aimed for functional restoration by coaptation of all main available motor and sensory nerves. We enumerate the technical challenges and postoperative complications and their management, including single episodes of acute rejection in two patients. At 6 months of follow-up, all facial allografts were surviving, facial appearance and function were improved, and glucocorticoids were successfully withdrawn in all patients.

Original language	English (US)
Pages (from-to)	715-722
Number of pages	8
Journal	New England Journal of Medicine
Volume	366
Issue number	8
DOIs	https://doi.org/10.1056/NEJMoa1111432
State	Published - Feb 23 2012

ASJC Scopus subject areas

General Medicine

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Pomahac, B., Pribaz, J., Eriksson, E., Bueno, E. M., Diaz-Siso, J. R., Rybicki, F. J., Annino, D. J., Orgill, D., Caterson, E. J., Caterson, S. A., Carty, M. J., Chun, Y. S., Sampson, C. E., Janis, J. E., Alam, D. S., Saavedra, A., Molnar, J. A., Edrich, T., Marty, F. M., & Tullius, S. G. (2012). Three patients with full facial transplantation. New England Journal of Medicine, 366(8), 715-722. https://doi.org/10.1056/NEJMoa1111432

Pomahac, B, Pribaz, J, Eriksson, E, Bueno, EM, Diaz-Siso, JR, Rybicki, FJ, Annino, DJ, Orgill, D, Caterson, EJ, Caterson, SA, Carty, MJ, Chun, YS, Sampson, CE, Janis, JE, Alam, DS, Saavedra, A, Molnar, JA, Edrich, T, Marty, FM & Tullius, SG 2012, 'Three patients with full facial transplantation', New England Journal of Medicine, vol. 366, no. 8, pp. 715-722. https://doi.org/10.1056/NEJMoa1111432

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title = "Three patients with full facial transplantation",

abstract = "Unlike conventional reconstruction, facial transplantation seeks to correct severe deformities in a single operation. We report on three patients who received full-face transplants at our institution in 2011 in operations that aimed for functional restoration by coaptation of all main available motor and sensory nerves. We enumerate the technical challenges and postoperative complications and their management, including single episodes of acute rejection in two patients. At 6 months of follow-up, all facial allografts were surviving, facial appearance and function were improved, and glucocorticoids were successfully withdrawn in all patients.",

author = "Bohdan Pomahac and Julian Pribaz and Elof Eriksson and Bueno, {Ericka M.} and Diaz-Siso, {J. Rodrigo} and Rybicki, {Frank J.} and Annino, {Donald J.} and Dennis Orgill and Caterson, {Edward J.} and Caterson, {Stephanie A.} and Carty, {Matthew J.} and Chun, {Yoon S.} and Sampson, {Christian E.} and Janis, {Jeffrey E.} and Alam, {Daniel S.} and Arturo Saavedra and Molnar, {Joseph A.} and Thomas Edrich and Marty, {Francisco M.} and Tullius, {Stefan G.}",

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AU - Rybicki, Frank J.

AU - Annino, Donald J.

AU - Orgill, Dennis

AU - Caterson, Edward J.

AU - Caterson, Stephanie A.

AU - Carty, Matthew J.

AU - Chun, Yoon S.

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AU - Alam, Daniel S.

AU - Saavedra, Arturo

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AU - Marty, Francisco M.

AU - Tullius, Stefan G.

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Three patients with full facial transplantation

Abstract

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