Thrombocytopenia in pregnancy

Ravindra Sarode, Eugene P. Frenkel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Thrombocytopenia is a common hematoloc1gical disorder that has classically been evaluated in an orderly clinical and laboratory approach. When thrombocytopenia is identified in the patient who is pregnant, important clinical differences and therapeutic implications exist when compared to the non-pregnant patient. These relate to the safety of the mother during pregnancy, viability of the fetus, the proper approach to parturition, and post-delivery care of the mother and the baby. The recognition of thrombocytopenia is quite common in pregnancy, occurring in nearly 10% of patients. An unusual aspect of most of these events is that the majority are physiological. Thus the term “gestational thrombocytopenia” has been applied to this group of patients. This physiologic event must be differentiated from the less common, but clinically significant occurrence of a pathological mechanism for the thrombocytopenia. Such pathologic events are commonly associated with an evident clinical presentation and are potentially serious issues in the maintenance of the pregnancy and the health of the mother. In some circumstances, the thrombocytopenia is actually part of a more complex clinical disorder. The causes of thrombocytopenia in pregnancy are delineated in Table 15.1. Gestational or physiological thrombocytopenia Clearly, the most common cause of thrombocytopenia in pregnancy is a physiological event, since it is seen in 5 to 7% of all pregnancies, and actually accounts for more than 75% of all cases of thrombocytopenia during pregnancy.

Original languageEnglish (US)
Title of host publicationHematological Complications in Obstetrics, Pregnancy, and Gynecology
PublisherCambridge University Press
Pages490-505
Number of pages16
ISBN (Print)9780511526978, 052183953X, 9780521839532
DOIs
StatePublished - Jan 1 2006

Fingerprint

Thrombocytopenia
Pregnancy
Mothers
Pregnancy Maintenance
Fetus
Parturition
Safety
Health

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sarode, R., & Frenkel, E. P. (2006). Thrombocytopenia in pregnancy. In Hematological Complications in Obstetrics, Pregnancy, and Gynecology (pp. 490-505). Cambridge University Press. https://doi.org/10.1017/CBO9780511526978.016

Thrombocytopenia in pregnancy. / Sarode, Ravindra; Frenkel, Eugene P.

Hematological Complications in Obstetrics, Pregnancy, and Gynecology. Cambridge University Press, 2006. p. 490-505.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sarode, R & Frenkel, EP 2006, Thrombocytopenia in pregnancy. in Hematological Complications in Obstetrics, Pregnancy, and Gynecology. Cambridge University Press, pp. 490-505. https://doi.org/10.1017/CBO9780511526978.016
Sarode R, Frenkel EP. Thrombocytopenia in pregnancy. In Hematological Complications in Obstetrics, Pregnancy, and Gynecology. Cambridge University Press. 2006. p. 490-505 https://doi.org/10.1017/CBO9780511526978.016
Sarode, Ravindra ; Frenkel, Eugene P. / Thrombocytopenia in pregnancy. Hematological Complications in Obstetrics, Pregnancy, and Gynecology. Cambridge University Press, 2006. pp. 490-505
@inbook{c3745350d1a846b4b7be1ebe2e9926da,
title = "Thrombocytopenia in pregnancy",
abstract = "Thrombocytopenia is a common hematoloc1gical disorder that has classically been evaluated in an orderly clinical and laboratory approach. When thrombocytopenia is identified in the patient who is pregnant, important clinical differences and therapeutic implications exist when compared to the non-pregnant patient. These relate to the safety of the mother during pregnancy, viability of the fetus, the proper approach to parturition, and post-delivery care of the mother and the baby. The recognition of thrombocytopenia is quite common in pregnancy, occurring in nearly 10{\%} of patients. An unusual aspect of most of these events is that the majority are physiological. Thus the term “gestational thrombocytopenia” has been applied to this group of patients. This physiologic event must be differentiated from the less common, but clinically significant occurrence of a pathological mechanism for the thrombocytopenia. Such pathologic events are commonly associated with an evident clinical presentation and are potentially serious issues in the maintenance of the pregnancy and the health of the mother. In some circumstances, the thrombocytopenia is actually part of a more complex clinical disorder. The causes of thrombocytopenia in pregnancy are delineated in Table 15.1. Gestational or physiological thrombocytopenia Clearly, the most common cause of thrombocytopenia in pregnancy is a physiological event, since it is seen in 5 to 7{\%} of all pregnancies, and actually accounts for more than 75{\%} of all cases of thrombocytopenia during pregnancy.",
author = "Ravindra Sarode and Frenkel, {Eugene P.}",
year = "2006",
month = "1",
day = "1",
doi = "10.1017/CBO9780511526978.016",
language = "English (US)",
isbn = "9780511526978",
pages = "490--505",
booktitle = "Hematological Complications in Obstetrics, Pregnancy, and Gynecology",
publisher = "Cambridge University Press",

}

TY - CHAP

T1 - Thrombocytopenia in pregnancy

AU - Sarode, Ravindra

AU - Frenkel, Eugene P.

PY - 2006/1/1

Y1 - 2006/1/1

N2 - Thrombocytopenia is a common hematoloc1gical disorder that has classically been evaluated in an orderly clinical and laboratory approach. When thrombocytopenia is identified in the patient who is pregnant, important clinical differences and therapeutic implications exist when compared to the non-pregnant patient. These relate to the safety of the mother during pregnancy, viability of the fetus, the proper approach to parturition, and post-delivery care of the mother and the baby. The recognition of thrombocytopenia is quite common in pregnancy, occurring in nearly 10% of patients. An unusual aspect of most of these events is that the majority are physiological. Thus the term “gestational thrombocytopenia” has been applied to this group of patients. This physiologic event must be differentiated from the less common, but clinically significant occurrence of a pathological mechanism for the thrombocytopenia. Such pathologic events are commonly associated with an evident clinical presentation and are potentially serious issues in the maintenance of the pregnancy and the health of the mother. In some circumstances, the thrombocytopenia is actually part of a more complex clinical disorder. The causes of thrombocytopenia in pregnancy are delineated in Table 15.1. Gestational or physiological thrombocytopenia Clearly, the most common cause of thrombocytopenia in pregnancy is a physiological event, since it is seen in 5 to 7% of all pregnancies, and actually accounts for more than 75% of all cases of thrombocytopenia during pregnancy.

AB - Thrombocytopenia is a common hematoloc1gical disorder that has classically been evaluated in an orderly clinical and laboratory approach. When thrombocytopenia is identified in the patient who is pregnant, important clinical differences and therapeutic implications exist when compared to the non-pregnant patient. These relate to the safety of the mother during pregnancy, viability of the fetus, the proper approach to parturition, and post-delivery care of the mother and the baby. The recognition of thrombocytopenia is quite common in pregnancy, occurring in nearly 10% of patients. An unusual aspect of most of these events is that the majority are physiological. Thus the term “gestational thrombocytopenia” has been applied to this group of patients. This physiologic event must be differentiated from the less common, but clinically significant occurrence of a pathological mechanism for the thrombocytopenia. Such pathologic events are commonly associated with an evident clinical presentation and are potentially serious issues in the maintenance of the pregnancy and the health of the mother. In some circumstances, the thrombocytopenia is actually part of a more complex clinical disorder. The causes of thrombocytopenia in pregnancy are delineated in Table 15.1. Gestational or physiological thrombocytopenia Clearly, the most common cause of thrombocytopenia in pregnancy is a physiological event, since it is seen in 5 to 7% of all pregnancies, and actually accounts for more than 75% of all cases of thrombocytopenia during pregnancy.

UR - http://www.scopus.com/inward/record.url?scp=84928430985&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84928430985&partnerID=8YFLogxK

U2 - 10.1017/CBO9780511526978.016

DO - 10.1017/CBO9780511526978.016

M3 - Chapter

AN - SCOPUS:84928430985

SN - 9780511526978

SN - 052183953X

SN - 9780521839532

SP - 490

EP - 505

BT - Hematological Complications in Obstetrics, Pregnancy, and Gynecology

PB - Cambridge University Press

ER -