Abstract
A 4-month-old girl initially presented to the pediatric ICU at 9 days old with multiorgan failure and cerebellar hemorrhage secondary to disseminated enteroviral infection and was eventually listed for liver transplant. Due to severe coagulopathy, she developed a hemothorax after line placement. Despite operative exploration and multiple recombinant factor VIIa doses, massive bleeding continued. The bleeding was finally controlled with thromboelastography-targeted platelet and cryoprecipitate transfusion in addition to four-factor prothrombin complex concentrate administration. This management strategy was invaluable in controlling bleeding from an iatrogenic cause.
Original language | English (US) |
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Pages (from-to) | 170-173 |
Number of pages | 4 |
Journal | Blood Coagulation and Fibrinolysis |
Volume | 31 |
Issue number | 2 |
DOIs | |
State | Published - Mar 1 2020 |
Externally published | Yes |
Keywords
- coagulopathy
- four-factor prothrombin complex concentrate
- liver failure
- thromboelastography
ASJC Scopus subject areas
- Hematology