Thrombotic thrombocytopenic purpura: 2012 American Society for Apheresis (ASFA) consensus conference on classification, diagnosis, management, and future research

Ravi Sarode, Nick Bandarenko, Mark E. Brecher, Joseph E. Kiss, Marisa B. Marques, Zbigniew M. Szczepiorkowski, Jeffrey L. Winters

Research output: Contribution to journalReview article

69 Scopus citations

Abstract

The American Society for Apheresis (ASFA) conducted a 1 day consensus conference on Thrombotic Thrombocytopenic Purpura (TTP) during its annual meeting in Atlanta, GA, on April 10, 2012. The authors of this article, a subcommittee of ASFA's Clinical Applications Committee, developed several questions with regard to definitions, classification, pathophysiology, diagnosis, management, and future research in TTP. These questions were provided to the seven invited speakers who are the experts in the field of TTP. Two moderators conducted the proceedings of the conference which was attended by more than 100 participants. After each presentation, there was an open discussion that included moderator-selected written questions submitted by the audience. A medical writer-generated transcript of the proceedings as well as each presentation was made available to the authors. Each summary was reviewed and approved by the respective speaker before submission of this article. The subcommittee also developed seven key questions for blinded, electronic polling conducted by the moderators to generate a consensus amongst the speakers. This article includes these presentation summaries as well as results of the electronic poll.

Original languageEnglish (US)
Pages (from-to)148-167
Number of pages20
JournalJournal of Clinical Apheresis
Volume29
Issue number3
DOIs
StatePublished - Jun 2014

Keywords

  • ADAMTS13
  • Upshaw Shulman Syndrome
  • microangiopathic hemolytic anemia
  • therapeutic plasma exchange
  • thrombotic thrombocytopenic purpura

ASJC Scopus subject areas

  • Hematology

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