Tightly regulated gene expression system in Salmonella enterica serovar Typhimurium

Jeffrey McKinney, Cecilia Guerrier-Takada, Jorge Galán, Sidney Altman

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A new Salmonella enterica serovar Typhimurium strain has been constructed to facilitate tightly regulated gene expression. Arabinose-inducible and glucose-repressible expression of a T7 RNA polymerase gene that has been integrated with an adjacent araC-PBAD control element into the bacterial chromosome allows dynamic control of T7 promoter-driven RNA transcription.

Original languageEnglish (US)
Pages (from-to)6056-6059
Number of pages4
JournalJournal of bacteriology
Volume184
Issue number21
DOIs
StatePublished - Nov 2002

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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