Time-course magnetic resonance imaging of rat pancreatic cyst after experimental pancreatitis

Yasunaga Seki, Satoru Naruse, Yoshiteru Seo, Motoji Kitagawa, Hiroshi Ishiguro, Youxue Wang, Masataka Murakami, Tetsuo Hayakawa

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Fast magnetic resonance (MR) imaging of the rat pancreas was carried out using a snapshot method to observe three-dimensional (3D) and temporal development of the pancreatic cyst after experimental pancreatitis. Acute pancreatitis was induced by a retrograde infusion of the trypsin-taurocholate solution into the pancreatic duct in 23 rats, of which seven survived for one month. Under 2% enflurane anesthesia, 1H images of the rat abdomen were taken by a 4.7 T magnetic resonance spectrometer under spontaneous breathing. 3D images of the pancreas and cyst were reconstructed from the axial, sagittal and coronal images taken before, 24 h, 7 days, 14 days, 21 days and 28 days after the induction of pancreatitis. The 3D images reconstructed from different slice orientations at each time point showed good agreement with each other. The calculated volumes of the cyst on 7th, 14th, 21st, and 28th day were 0.3 ± 0.1, 0.8 ± 0.3, 2.1 ± 0.6, 6.5 ± 1.3 mL, respectively. The cystic fluid volume on 28th day was 6.4 ± 1.4 mL, which confirmed reliability of volume measurement by MR imaging. Fast MR imaging (snapshot) together with 3D reconstruction allows us to understand the detailed chronological and spatial development of pancreatic cyst after acute pancreatitis in rats. (C) 2000 Elsevier Science Inc.

Original languageEnglish (US)
Pages (from-to)1003-1010
Number of pages8
JournalMagnetic Resonance Imaging
Volume18
Issue number8
DOIs
StatePublished - 2000

Fingerprint

Pancreatic Cyst
cysts
Magnetic resonance
Pancreatitis
rats
magnetic resonance
Rats
Magnetic Resonance Imaging
Imaging techniques
pancreas
Cysts
Pancreas
Magnetic resonance spectrometers
anesthesia
trypsin
Volume measurement
Enflurane
abdomen
Taurocholic Acid
Pancreatic Ducts

Keywords

  • 3D reconstruction
  • Experimental pancreatitis
  • Pancreatic cyst
  • Rat
  • Snapshot

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Seki, Y., Naruse, S., Seo, Y., Kitagawa, M., Ishiguro, H., Wang, Y., ... Hayakawa, T. (2000). Time-course magnetic resonance imaging of rat pancreatic cyst after experimental pancreatitis. Magnetic Resonance Imaging, 18(8), 1003-1010. https://doi.org/10.1016/S0730-725X(00)00203-4

Time-course magnetic resonance imaging of rat pancreatic cyst after experimental pancreatitis. / Seki, Yasunaga; Naruse, Satoru; Seo, Yoshiteru; Kitagawa, Motoji; Ishiguro, Hiroshi; Wang, Youxue; Murakami, Masataka; Hayakawa, Tetsuo.

In: Magnetic Resonance Imaging, Vol. 18, No. 8, 2000, p. 1003-1010.

Research output: Contribution to journalArticle

Seki, Y, Naruse, S, Seo, Y, Kitagawa, M, Ishiguro, H, Wang, Y, Murakami, M & Hayakawa, T 2000, 'Time-course magnetic resonance imaging of rat pancreatic cyst after experimental pancreatitis', Magnetic Resonance Imaging, vol. 18, no. 8, pp. 1003-1010. https://doi.org/10.1016/S0730-725X(00)00203-4
Seki, Yasunaga ; Naruse, Satoru ; Seo, Yoshiteru ; Kitagawa, Motoji ; Ishiguro, Hiroshi ; Wang, Youxue ; Murakami, Masataka ; Hayakawa, Tetsuo. / Time-course magnetic resonance imaging of rat pancreatic cyst after experimental pancreatitis. In: Magnetic Resonance Imaging. 2000 ; Vol. 18, No. 8. pp. 1003-1010.
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