Time to move the fat

Benjamin P. Weaver; Aileen K. Sewell; Min Han

doi:10.1101/gad.285460.116

Time to move the fat

Benjamin P. Weaver, Aileen K. Sewell, Min Han

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

In this issue of Genes & Development, Dowen and colleagues (pp. 1515-1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobilization at the transition to adulthood in Caenorhabditis elegans. This novel connection involves cross-tissue signaling fromthe hypodermis (epidermis) to the intestine to promote reproductive success in the germline.

Original language	English (US)
Pages (from-to)	1481-1482
Number of pages	2
Journal	Genes and Development
Volume	30
Issue number	13
DOIs	https://doi.org/10.1101/gad.285460.116
State	Published - Jul 1 2016
Externally published	Yes

Keywords

Fat metabolism
Insulin
MTORC2
MicroRNAs
Pqm-1
Vitellogenesis

ASJC Scopus subject areas

Genetics
Developmental Biology

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10.1101/gad.285460.116

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title = "Time to move the fat",

abstract = "In this issue of Genes & Development, Dowen and colleagues (pp. 1515-1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobilization at the transition to adulthood in Caenorhabditis elegans. This novel connection involves cross-tissue signaling fromthe hypodermis (epidermis) to the intestine to promote reproductive success in the germline.",

keywords = "Fat metabolism, Insulin, MTORC2, MicroRNAs, Pqm-1, Vitellogenesis",

author = "Weaver, {Benjamin P.} and Sewell, {Aileen K.} and Min Han",

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AU - Weaver, Benjamin P.

AU - Sewell, Aileen K.

AU - Han, Min

PY - 2016/7/1

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AB - In this issue of Genes & Development, Dowen and colleagues (pp. 1515-1528) elegantly unify two previously unconnected aspects of physiology. The investigators provide significant genetic evidence to support a critical link between developmental timing decisions and the regulation of lipid mobilization at the transition to adulthood in Caenorhabditis elegans. This novel connection involves cross-tissue signaling fromthe hypodermis (epidermis) to the intestine to promote reproductive success in the germline.

KW - Fat metabolism

KW - Insulin

KW - MTORC2

KW - MicroRNAs

KW - Pqm-1

KW - Vitellogenesis

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JO - Genes and Development

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Time to move the fat

Abstract

Keywords

ASJC Scopus subject areas

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