Tissue classifications in Monte Carlo simulations of patient dose for photon beam tumor treatments

Mu Han Lin, Tsi Chian Chao, Chung Chi Lee, Joseph Tung Chieh Chang, Chuan Jong Tung

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The purpose of this work was to study the calculated dose uncertainties induced by the material classification that determined the interaction cross-sections and the water-to-material stopping-power ratios. Calculations were made for a head- and neck-cancer patient treated with five intensity-modulated radiotherapy fields using 6MV photon beams. The patient's CT images were reconstructed into two voxelized patient phantoms based on different CT-to-material classification schemes. Comparisons of the depth-dose curve of the anterior-to-posterior field and the dose-volume-histogram of the treatment plan were used to evaluate the dose uncertainties from such schemes. The results indicated that any misassignment of tissue materials could lead to a substantial dose difference, which would affect the treatment outcome. To assure an appropriate material assignment, it is desirable to have different conversion tables for various parts of the body. The assignment of stopping-power ratio should be based on the chemical composition and the density of the material.

Original languageEnglish (US)
Pages (from-to)393-396
Number of pages4
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume619
Issue number1-3
DOIs
StatePublished - Jul 1 2010

Fingerprint

photon beams
Dosimetry
Tumors
tumors
Photons
Tissue
dosage
stopping power
simulation
conversion tables
histograms
Radiotherapy
radiation therapy
chemical composition
cancer
Monte Carlo simulation
cross sections
curves
water
Chemical analysis

Keywords

  • Material classification
  • Stopping-power ratio

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Instrumentation

Cite this

Tissue classifications in Monte Carlo simulations of patient dose for photon beam tumor treatments. / Lin, Mu Han; Chao, Tsi Chian; Lee, Chung Chi; Chang, Joseph Tung Chieh; Tung, Chuan Jong.

In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 619, No. 1-3, 01.07.2010, p. 393-396.

Research output: Contribution to journalArticle

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AB - The purpose of this work was to study the calculated dose uncertainties induced by the material classification that determined the interaction cross-sections and the water-to-material stopping-power ratios. Calculations were made for a head- and neck-cancer patient treated with five intensity-modulated radiotherapy fields using 6MV photon beams. The patient's CT images were reconstructed into two voxelized patient phantoms based on different CT-to-material classification schemes. Comparisons of the depth-dose curve of the anterior-to-posterior field and the dose-volume-histogram of the treatment plan were used to evaluate the dose uncertainties from such schemes. The results indicated that any misassignment of tissue materials could lead to a substantial dose difference, which would affect the treatment outcome. To assure an appropriate material assignment, it is desirable to have different conversion tables for various parts of the body. The assignment of stopping-power ratio should be based on the chemical composition and the density of the material.

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