Tm(DOTP)5-: A 23Na+ shift agent for perfused rat hearts

D. C. Buster, M. M C A Castro, C. F G C Geraldes, C. R. Malloy, A. D. Sherry, T. C. Siemers

Research output: Contribution to journalArticle

112 Scopus citations


Tm(DOTP)5-, the thulium(III) complex of 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''- tetra(methylenephosphonate), is introduced as a 23Na+ shift agent for use in discrimination of the NMR resonances of intra- and extracellular 23Na+ ions in perfused rat hearts. The novel shift agent is directly compared to the widely used Dy(TTHA)3- (dysprosium(III) triethylenetetraminehexaacetate).

Original languageEnglish (US)
Pages (from-to)25-32
Number of pages8
JournalMagnetic Resonance in Medicine
Issue number1
Publication statusPublished - 1990


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Buster, D. C., Castro, M. M. C. A., Geraldes, C. F. G. C., Malloy, C. R., Sherry, A. D., & Siemers, T. C. (1990). Tm(DOTP)5-: A 23Na+ shift agent for perfused rat hearts. Magnetic Resonance in Medicine, 15(1), 25-32.