Topical Review: Use of Fetal Tissue in Foot and Ankle Surgery

Andrew E. Hanselman; Trapper A J Lalli; Robert D. Santrock

doi:10.1177/1938640015578513

Topical Review: Use of Fetal Tissue in Foot and Ankle Surgery

Andrew E. Hanselman, Trapper A J Lalli, Robert D. Santrock

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Fetal tissues are well known for their therapeutic potential. They contain numerous growth factors, cytokines, and matrix components that promote regeneration of tissues while downregulating inflammation and scar formation. As a result, use of these treatments has expanded over the previous 20 years throughout various surgical specialties, including orthopaedics. With improved methods of sterilization, processing, and storage, surgeons need to be informed about the potential benefits of fetal tissue in foot and ankle surgery. The aim of this review is to provide a brief historical background, basic anatomy and physiology, and a current review of the literature in regard to chronic wounds, diabetic foot ulcerations, plantar fasciitis, tendon repair, adhesion prevention, nerve repair, and bone healing. Levels of Evidence: Level V: Expert Opinion

Original language	English (US)
Pages (from-to)	297-304
Number of pages	8
Journal	Foot and Ankle Specialist
Volume	8
Issue number	4
DOIs	https://doi.org/10.1177/1938640015578513
State	Published - Jan 1 2015

Keywords

amniotic membrane
chorionic membrane
fetal tissue
placenta
umbilical cord

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Surgery
Podiatry
Medicine(all)

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10.1177/1938640015578513

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