Total intravenous anesthesia with propofol for transsternal thymectomy in myasthenia gravis

David O'Flaherty, John H. Pennant, Krishna Rao, Adolf H. Giesecke

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Patients with myasthenia gravis (MG) represent a significant management problem for the anesthesiologist. Anesthetic concerns center on the MG patient's unpredictable response to muscle relaxants and increased susceptibility to postoperative respiratory failure, resulting in prolonged dependence on mechanical ventilation. We describe the first reported use of total intravenous anesthesia with propofol to provide satisfactory surgical conditions in two patients with MG undergoing transsternal thymectomy. Propofol is a suitable drug for intubation and continuous infusion anesthesia, allowing fine control of anesthetic depth, good operating conditions, and a recovery profile suitable for MG patients undergoing surgery.

Original languageEnglish (US)
Pages (from-to)241-244
Number of pages4
JournalJournal of Clinical Anesthesia
Volume4
Issue number3
DOIs
StatePublished - 1992

Fingerprint

Intravenous Anesthesia
Thymectomy
Myasthenia Gravis
Propofol
Anesthetics
Artificial Respiration
Intubation
Respiratory Insufficiency
Anesthesia
Muscles
Pharmaceutical Preparations

Keywords

  • anesthesia, intravenous
  • myasthenia gravis
  • Propofol
  • thymectomy, transsternal

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Total intravenous anesthesia with propofol for transsternal thymectomy in myasthenia gravis. / O'Flaherty, David; Pennant, John H.; Rao, Krishna; Giesecke, Adolf H.

In: Journal of Clinical Anesthesia, Vol. 4, No. 3, 1992, p. 241-244.

Research output: Contribution to journalArticle

O'Flaherty, David ; Pennant, John H. ; Rao, Krishna ; Giesecke, Adolf H. / Total intravenous anesthesia with propofol for transsternal thymectomy in myasthenia gravis. In: Journal of Clinical Anesthesia. 1992 ; Vol. 4, No. 3. pp. 241-244.
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