Toward noninvasive characterization of breast cancer and cancer metabolism with diffuse optics

David R. Busch, Regine Choe, Turgut Durduran, Arjun G. Yodh

Research output: Contribution to journalReview article

27 Scopus citations


This article reviews recent developments in diffuse optical imaging and monitoring of breast cancer, that is, optical mammography. Optical mammography permits noninvasive, safe, and frequent measurement of tissue hemodynamics, oxygen metabolism, and components (lipids, water, and so forth), the development of new compound indices indicative of cancer risk and malignancy, and holds potential for frequent noninvasive longitudinal monitoring of therapy progression.

Original languageEnglish (US)
Pages (from-to)345-365
Number of pages21
JournalPET Clinics
Issue number3
StatePublished - Jul 1 2013



  • Blood flow
  • Breast cancer
  • Diffuse optical spectroscopy
  • Diffuse optical tomography
  • Metabolic imaging
  • Neoadjuvant chemotherapy

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging

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