TY - JOUR
T1 - Toward noninvasive characterization of breast cancer and cancer metabolism with diffuse optics
AU - Busch, David R.
AU - Choe, Regine
AU - Durduran, Turgut
AU - Yodh, Arjun G.
N1 - Funding Information:
A.G.Y. gratefully acknowledges partial support from the National Institutes of Health through grants CA087971 , NS060653 , EB002109 , and EB015893 .
Funding Information:
T.D. gratefully acknowledges partial support by Fundació Cellex Barcelona , Marie Curie IRG ( FP7 , RPTAMON ), Institute de Salud Carlos III (DOM-MON, FIS), Ministerio de Ciencia e Innovación (MICINN) , Ministerio de Economía y Comepetitividad , Institució CERCA (DOCNEURO, PROVAT-002-11), Generalitat de Catalunya , European Regional Development Fund (FEDER/ERDF) and LASERLAB ( FP7 ) and Photonics4Life ( FP7 ) consortia.
Funding Information:
R.C. gratefully acknowledges support from the National Institutes of Health through K99/R00-CA126187 .
Funding Information:
D.R.B. gratefully acknowledges partial support from the Thrasher Research Fund and National Institutes of Health through grant NS072338 .
PY - 2013/7
Y1 - 2013/7
N2 - This article reviews recent developments in diffuse optical imaging and monitoring of breast cancer, that is, optical mammography. Optical mammography permits noninvasive, safe, and frequent measurement of tissue hemodynamics, oxygen metabolism, and components (lipids, water, and so forth), the development of new compound indices indicative of cancer risk and malignancy, and holds potential for frequent noninvasive longitudinal monitoring of therapy progression.
AB - This article reviews recent developments in diffuse optical imaging and monitoring of breast cancer, that is, optical mammography. Optical mammography permits noninvasive, safe, and frequent measurement of tissue hemodynamics, oxygen metabolism, and components (lipids, water, and so forth), the development of new compound indices indicative of cancer risk and malignancy, and holds potential for frequent noninvasive longitudinal monitoring of therapy progression.
KW - Blood flow
KW - Breast cancer
KW - Diffuse optical spectroscopy
KW - Diffuse optical tomography
KW - Metabolic imaging
KW - Neoadjuvant chemotherapy
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U2 - 10.1016/j.cpet.2013.04.004
DO - 10.1016/j.cpet.2013.04.004
M3 - Review article
C2 - 24244206
AN - SCOPUS:84879597340
SN - 1556-8598
VL - 8
SP - 345
EP - 365
JO - PET Clinics
JF - PET Clinics
IS - 3
ER -