Toward single breath-hold whole-heart coverage coronary MRA using highly accelerated parallel imaging with a 32-channel MR system

Thoralf Niendorf, Christopher J. Hardy, Randy O. Giaquinto, Patrick Gross, Harvey E. Cline, Yudong Zhu, Gontran Kenwood, Shmuel Cohen, Aaron K. Grant, Sanjay Joshi, Neil M. Rofsky, Daniel K. Sodickson

Research output: Contribution to journalArticle

96 Scopus citations

Abstract

Coronary MR angiography (CURA) is generally confined to the acquisition of multiple targeted slabs with coverage dictated by the competing constraints of signal-to-noise ratio (SNR), physiological motion, and scan time. This work addresses these obstacles by demonstrating the technical feasibility of using a 32-channel coil array and receiver system for highly accelerated volumetric breath-hold CMRA. The use of the 32-element array in unaccelerated CMRA studies provided a baseline SNR increase of as much as 40% over conventional cardiac-optimized phased array coils, which resulted in substantially enhanced image quality and improved delineation of the coronary arteries. Modest accelerations were used to reduce breath-hold durations for tailored coverage of the coronary arteries using targeted multi-oblique slabs to as little as 10 s. Finally, high net accelerations were combined with the SNR advantages of a 3D steady-state free precession (SSFP) technique to achieve previously unattainable comprehensive volumetric coverage of the coronary arteries in a single breath-hold. The merits and limitations of this simplified volumetric imaging approach are discussed and its implications for coronary MRA are considered.

Original languageEnglish (US)
Pages (from-to)167-176
Number of pages10
JournalMagnetic resonance in medicine
Volume56
Issue number1
DOIs
StatePublished - Jul 1 2006

Keywords

  • Breath-hold
  • Coronary magnetic resonance angiography (CMRA)
  • Parallel imaging
  • Signal-to-noise ratio (SNR)
  • Whole-heart coverage

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Niendorf, T., Hardy, C. J., Giaquinto, R. O., Gross, P., Cline, H. E., Zhu, Y., Kenwood, G., Cohen, S., Grant, A. K., Joshi, S., Rofsky, N. M., & Sodickson, D. K. (2006). Toward single breath-hold whole-heart coverage coronary MRA using highly accelerated parallel imaging with a 32-channel MR system. Magnetic resonance in medicine, 56(1), 167-176. https://doi.org/10.1002/mrm.20923