Trace metals in hematopoiesis

C. J. Deur, M. J. Stone, E. P. Frenkel

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

The trace metals represent an extremely small part of the total mass of the organism. In spite of this, these elements appear to play major roles in metabolism. At the level of the hematopoietic system, specific roles can be identified for iron, copper, zinc, and cobalt. Other trace metals appear to play less clearly defined roles in hematopoiesis but clearly are involved by virtue of a number of interactions at the level of absorption, intermediary metabolism, or modulation of toxicity. Still other trace metals, such as lithium, appear to have a therapeutic role in altering production of granulocytes, by an as yet unidentified mechanism.

Original languageEnglish (US)
Pages (from-to)309-331
Number of pages23
JournalAmerican Journal of Hematology
Volume11
Issue number3
DOIs
StatePublished - Nov 1981

Keywords

  • copper
  • hematopoiesis
  • trace metals
  • zinc

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'Trace metals in hematopoiesis'. Together they form a unique fingerprint.

  • Cite this

    Deur, C. J., Stone, M. J., & Frenkel, E. P. (1981). Trace metals in hematopoiesis. American Journal of Hematology, 11(3), 309-331. https://doi.org/10.1002/ajh.2830110313