Trace metals in hematopoiesis

C. J. Deur, M. J. Stone, E. P. Frenkel

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The trace metals represent an extremely small part of the total mass of the organism. In spite of this, these elements appear to play major roles in metabolism. At the level of the hematopoietic system, specific roles can be identified for iron, copper, zinc, and cobalt. Other trace metals appear to play less clearly defined roles in hematopoiesis but clearly are invovled by virtue of a number of interactions at the level of absorption, intermediary metabolism, or modulation of toxicity. Still other trace metals, such as lithium, appear to have a therapeutic role in altering production of granulocytes, by an as yet unidentified mechanism.

Original languageEnglish (US)
Pages (from-to)309-331
Number of pages23
JournalAmerican Journal of Hematology
Volume11
Issue number3
StatePublished - 1981

Fingerprint

Hematopoiesis
Metals
Hematopoietic System
Cobalt
Lithium
Granulocytes
Zinc
Copper
Iron
Therapeutics

ASJC Scopus subject areas

  • Hematology

Cite this

Deur, C. J., Stone, M. J., & Frenkel, E. P. (1981). Trace metals in hematopoiesis. American Journal of Hematology, 11(3), 309-331.

Trace metals in hematopoiesis. / Deur, C. J.; Stone, M. J.; Frenkel, E. P.

In: American Journal of Hematology, Vol. 11, No. 3, 1981, p. 309-331.

Research output: Contribution to journalArticle

Deur, CJ, Stone, MJ & Frenkel, EP 1981, 'Trace metals in hematopoiesis', American Journal of Hematology, vol. 11, no. 3, pp. 309-331.
Deur CJ, Stone MJ, Frenkel EP. Trace metals in hematopoiesis. American Journal of Hematology. 1981;11(3):309-331.
Deur, C. J. ; Stone, M. J. ; Frenkel, E. P. / Trace metals in hematopoiesis. In: American Journal of Hematology. 1981 ; Vol. 11, No. 3. pp. 309-331.
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