Train of four monitoring device

Anastasia Karapanagou; Nicholas R. Bergstrom; Christopher Beauregard; Kyler B. Dillon; Jeanine L.M. Skorinko; Ahmet Can Sabuncu; Eric B. Rosero

doi:10.1115/DMD2020-9038

Train of four monitoring device

Anastasia Karapanagou, Nicholas R. Bergstrom, Christopher Beauregard, Kyler B. Dillon, Jeanine L.M. Skorinko, Ahmet Can Sabuncu, Eric B. Rosero

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Assessment of neuromuscular blockade during anesthesia is achieved using the Train of Four (TOF) monitoring technique. However, current devices are limited to conditions in which the hand can move freely during operation. The goal of this project was to design, prototype, and test a device which extends the TOF technique to conditions where movement is restricted. Interviews were conducted with stakeholders to better understand the need for this device and to get feedback on preliminary designs. The resulting device consists of a thumb-mounted balloon, which converts the force due to thumb twitches into pressure, which then acts as the physical analog to muscle response. This pressure is transduced and analyzed to produce a TOF count and TOF ratio. A prototype was constructed and tested on human subjects with different hand geometries.

Original language	English (US)
Title of host publication	Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020
Publisher	American Society of Mechanical Engineers (ASME)
ISBN (Electronic)	9780791883549
DOIs	https://doi.org/10.1115/DMD2020-9038
State	Published - 2020
Externally published	Yes
Event	2020 Design of Medical Devices Conference, DMD 2020 - Minneapolis, United States Duration: Apr 6 2020 → Apr 9 2020

Publication series

Name	Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020

Conference

Conference	2020 Design of Medical Devices Conference, DMD 2020
Country/Territory	United States
City	Minneapolis
Period	4/6/20 → 4/9/20

Keywords

Medical device
Monitoring
Neuromuscular blockade
Train of Four

ASJC Scopus subject areas

Biomedical Engineering

Access to Document

10.1115/DMD2020-9038

Cite this

Karapanagou, A., Bergstrom, N. R., Beauregard, C., Dillon, K. B., Skorinko, J. L. M., Sabuncu, A. C., & Rosero, E. B. (2020). Train of four monitoring device. In Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020 (Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/DMD2020-9038

Train of four monitoring device. / Karapanagou, Anastasia; Bergstrom, Nicholas R.; Beauregard, Christopher et al.
Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020. American Society of Mechanical Engineers (ASME), 2020. (Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Karapanagou, A, Bergstrom, NR, Beauregard, C, Dillon, KB, Skorinko, JLM, Sabuncu, AC & Rosero, EB 2020, Train of four monitoring device. in Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020. Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020, American Society of Mechanical Engineers (ASME), 2020 Design of Medical Devices Conference, DMD 2020, Minneapolis, United States, 4/6/20. https://doi.org/10.1115/DMD2020-9038

Karapanagou A, Bergstrom NR, Beauregard C, Dillon KB, Skorinko JLM, Sabuncu AC et al. Train of four monitoring device. In Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020. American Society of Mechanical Engineers (ASME). 2020. (Frontiers in Biomedical Devices, BIOMED - 2020 Design of Medical Devices Conference, DMD 2020). doi: 10.1115/DMD2020-9038

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abstract = "Assessment of neuromuscular blockade during anesthesia is achieved using the Train of Four (TOF) monitoring technique. However, current devices are limited to conditions in which the hand can move freely during operation. The goal of this project was to design, prototype, and test a device which extends the TOF technique to conditions where movement is restricted. Interviews were conducted with stakeholders to better understand the need for this device and to get feedback on preliminary designs. The resulting device consists of a thumb-mounted balloon, which converts the force due to thumb twitches into pressure, which then acts as the physical analog to muscle response. This pressure is transduced and analyzed to produce a TOF count and TOF ratio. A prototype was constructed and tested on human subjects with different hand geometries.",

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AU - Sabuncu, Ahmet Can

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AB - Assessment of neuromuscular blockade during anesthesia is achieved using the Train of Four (TOF) monitoring technique. However, current devices are limited to conditions in which the hand can move freely during operation. The goal of this project was to design, prototype, and test a device which extends the TOF technique to conditions where movement is restricted. Interviews were conducted with stakeholders to better understand the need for this device and to get feedback on preliminary designs. The resulting device consists of a thumb-mounted balloon, which converts the force due to thumb twitches into pressure, which then acts as the physical analog to muscle response. This pressure is transduced and analyzed to produce a TOF count and TOF ratio. A prototype was constructed and tested on human subjects with different hand geometries.

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Train of four monitoring device

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

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