Trans alkenes by stereoselective reduction of α-Ph2PO ketones: E-isosaffrole, E-anethole, and peniculin

Antony D. Buss, Ralph Mason, Stuart Warren

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Conditions are described for the stereoselective reduction of α-Ph2PO ketones and stereospecific elimination from the resulting threo Horner-Wittig intermediates to give pure E-alkenes such as the title compounds.

Original languageEnglish (US)
Pages (from-to)5293-5296
Number of pages4
JournalTetrahedron Letters
Volume24
Issue number47
DOIs
StatePublished - 1983

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Alkenes
Ketones
anethole

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Trans alkenes by stereoselective reduction of α-Ph2PO ketones : E-isosaffrole, E-anethole, and peniculin. / Buss, Antony D.; Mason, Ralph; Warren, Stuart.

In: Tetrahedron Letters, Vol. 24, No. 47, 1983, p. 5293-5296.

Research output: Contribution to journalArticle

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abstract = "Conditions are described for the stereoselective reduction of α-Ph2PO ketones and stereospecific elimination from the resulting threo Horner-Wittig intermediates to give pure E-alkenes such as the title compounds.",
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AU - Warren, Stuart

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