Transcription control by long non-coding RNAs

Tyler Faust, Alan D. Frankel, Iván D'Orso

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Non-coding RNAs have been found to regulate many cellular processes and thus expand the functional genetic repertoire contained within the genome. With the recent advent of genomic tools, it is now evident that these RNA molecules play central regulatory roles in many transcriptional programs. Here we discuss how they are targeted to promoters in several cases and how they operate at specific points in the transcription cycle to precisely control gene expression.

Original languageEnglish (US)
Pages (from-to)78-86
Number of pages9
JournalTranscription
Volume3
Issue number2
DOIs
StatePublished - Mar 2012

Fingerprint

Long Noncoding RNA
Untranslated RNA
Transcription
Gene expression
Genes
Genome
RNA
Gene Expression
Molecules

Keywords

  • Chromatin
  • Epigenetic silencing
  • Large intergenic non-coding RNAs
  • Long non-coding RNAs
  • RNA polymerase ii
  • Transcription

ASJC Scopus subject areas

  • Biochemistry
  • Biotechnology
  • Genetics

Cite this

Transcription control by long non-coding RNAs. / Faust, Tyler; Frankel, Alan D.; D'Orso, Iván.

In: Transcription, Vol. 3, No. 2, 03.2012, p. 78-86.

Research output: Contribution to journalArticle

Faust, Tyler ; Frankel, Alan D. ; D'Orso, Iván. / Transcription control by long non-coding RNAs. In: Transcription. 2012 ; Vol. 3, No. 2. pp. 78-86.
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