Transforming growth factor β and the immunopathologic assessment of tolerance

Jose R. Torrealba; William J. Burlingham

doi:10.1097/01.mot.0000130144.06730.ea

Transforming growth factor β and the immunopathologic assessment of tolerance

Jose R. Torrealba, William J. Burlingham

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Data implicating TGF-β in the development of active peripheral tolerance by T regulatory cells is increasing. In organ transplantation, the peripheral and intragraft TGF-β status as well as the functional and histologic characterization of intragraft T regulatory cells by TGF-β may provide important steps toward a tolerance assay to monitor allograft recipients.

Original language	English (US)
Pages (from-to)	241-245
Number of pages	5
Journal	Current opinion in organ transplantation
Volume	9
Issue number	3
DOIs	https://doi.org/10.1097/01.mot.0000130144.06730.ea
State	Published - 2004

Keywords

T regulatory cells
Tolerance
Transforming growth factor β
Transplantation

ASJC Scopus subject areas

Immunology and Allergy
Transplantation

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10.1097/01.mot.0000130144.06730.ea

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title = "Transforming growth factor β and the immunopathologic assessment of tolerance",

abstract = "Data implicating TGF-β in the development of active peripheral tolerance by T regulatory cells is increasing. In organ transplantation, the peripheral and intragraft TGF-β status as well as the functional and histologic characterization of intragraft T regulatory cells by TGF-β may provide important steps toward a tolerance assay to monitor allograft recipients.",

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AB - Data implicating TGF-β in the development of active peripheral tolerance by T regulatory cells is increasing. In organ transplantation, the peripheral and intragraft TGF-β status as well as the functional and histologic characterization of intragraft T regulatory cells by TGF-β may provide important steps toward a tolerance assay to monitor allograft recipients.

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KW - Transplantation

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Transforming growth factor β and the immunopathologic assessment of tolerance

Abstract

Keywords

ASJC Scopus subject areas

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