Translational regulation of the plant S-adenosylmethionine decarboxylase

C. Hanfrey, M. Franceschetti, M. J. Mayer, C. Illingworth, K. Elliott, M. Collier, B. Thompson, B. Perry, A. J. Michael

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

It is becoming apparent that control of protein synthesis by metabolites is more common than previously thought. Much of that control is exerted at the level of initiation of mRNA translation, orchestrated by upstream open reading frames (uORFs) and RNA secondary structure. S-Adenosylmethionine decarboxylase (AdoMetDC) is a key enzyme in polyamine biosynthesis and both mammalian and plant AdoMetDCs are translationally regulated by uORFs in response to polyamine levels by distinct mechanisms.

Original languageEnglish (US)
Pages (from-to)424-427
Number of pages4
JournalBiochemical Society Transactions
Volume31
Issue number2
DOIs
StatePublished - Apr 2003

Fingerprint

Adenosylmethionine Decarboxylase
Polyamines
Open Reading Frames
Biosynthesis
Protein Biosynthesis
Metabolites
RNA
Messenger RNA
Enzymes
Proteins

Keywords

  • Polyamine
  • S-adenosylmethionine decarboxylase
  • Translation initiation
  • Upstream open reading frame

ASJC Scopus subject areas

  • Biochemistry

Cite this

Hanfrey, C., Franceschetti, M., Mayer, M. J., Illingworth, C., Elliott, K., Collier, M., ... Michael, A. J. (2003). Translational regulation of the plant S-adenosylmethionine decarboxylase. Biochemical Society Transactions, 31(2), 424-427. https://doi.org/10.1042/BST0310424

Translational regulation of the plant S-adenosylmethionine decarboxylase. / Hanfrey, C.; Franceschetti, M.; Mayer, M. J.; Illingworth, C.; Elliott, K.; Collier, M.; Thompson, B.; Perry, B.; Michael, A. J.

In: Biochemical Society Transactions, Vol. 31, No. 2, 04.2003, p. 424-427.

Research output: Contribution to journalArticle

Hanfrey, C, Franceschetti, M, Mayer, MJ, Illingworth, C, Elliott, K, Collier, M, Thompson, B, Perry, B & Michael, AJ 2003, 'Translational regulation of the plant S-adenosylmethionine decarboxylase', Biochemical Society Transactions, vol. 31, no. 2, pp. 424-427. https://doi.org/10.1042/BST0310424
Hanfrey C, Franceschetti M, Mayer MJ, Illingworth C, Elliott K, Collier M et al. Translational regulation of the plant S-adenosylmethionine decarboxylase. Biochemical Society Transactions. 2003 Apr;31(2):424-427. https://doi.org/10.1042/BST0310424
Hanfrey, C. ; Franceschetti, M. ; Mayer, M. J. ; Illingworth, C. ; Elliott, K. ; Collier, M. ; Thompson, B. ; Perry, B. ; Michael, A. J. / Translational regulation of the plant S-adenosylmethionine decarboxylase. In: Biochemical Society Transactions. 2003 ; Vol. 31, No. 2. pp. 424-427.
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