Abstract

Transverse myelitis (TM) includes a pathobiologically heterogeneous syndrome characterized by acute or subacute spinal cord dysfunction resulting in paresis, a sensory level, and autonomic (bladder, bowel, and sexual) impairment below the level of the lesion. Etiologies for TM can be broadly classified as parainfectious, paraneoplastic, drug/toxin-induced, systemic autoimmune disorders, and acquired demyelinating diseases. We discuss the clinical evaluation, workup, and acute and long-term management of patients with TM. Additionally, we briefly discuss various disease entities that may cause TM and their salient distinguishing features, as well as disorders that may mimic TM.

Original languageEnglish (US)
Pages (from-to)79-138
Number of pages60
JournalNeurologic Clinics
Volume31
Issue number1
DOIs
StatePublished - Feb 1 2013

Keywords

  • Idiopathic transverse myelitis
  • Longitudinally-extensive transverse myelitis
  • Lupus myelopathy
  • Multiple sclerosis
  • Sjogren's myelopathy
  • Transverse myelitis

ASJC Scopus subject areas

  • Clinical Neurology

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