Treatment and Survival Disparities of Colon Cancer in the Texas-Mexico Border Population: Cancer Disparities in Border Population

Justin Yan, Caitlin A. Hester, Hong Zhu, Jingsheng Yan, Matthew M. Augustine, Matthew R. Porembka, Sam C. Wang, John C. Mansour, Herbert J.Zeh III, Adam C. Yopp, Patricio M. Polanco

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Previous studies have reported healthcare disparities in the Texas-Mexico border population. Our aim was to evaluate treatment utilization and oncologic outcomes of colon cancer patients in this vulnerable population. Methods: Patients with localized and regional colon cancer (CC) were identified in the Texas Cancer Registry (1995-2016). Clinicopathological data, hospital factors, receipt of optimal treatment, and overall survival (OS) were compared between Texas-Mexico Border (TMB) and the Non-Texas-Mexico Border (NTMB) cohorts. Multivariable analysis was performed to identify risk factors associated with decreased survival. Results: We identified 43,557 patients with localized/regional CC (9% TMB and 91% NTMB). TMB patients were more likely to be Hispanic (73% versus 13%), less likely to have private insurance (13% versus 21%), were more often treated at safety net hospitals (82% versus 22%) and less likely at ACS-CoC accredited hospitals (32% versus 57%). TMB patients were more likely to receive suboptimal treatment (21% versus 16%) and had a lower median OS for localized (8.58 versus 9.58 y) and regional colon cancer (5.75 versus 6.18 y, all P < 0.001). In multivariable analysis, TMB status was not associated with worse OS. Factors associated with worse survival included receipt of suboptimal treatment, Medicare/insured status, and treatment in safety net and non-accredited ACS-CoC hospitals (all P < 0.001) Conclusions: While TMB CC patients had worse OS, TMB status itself was not found to be a risk factor for decreased survival. This survival disparity is likely associated with higher rate of suboptimal treatment, Medicare/Uninsured status, and decreased access to ACS-CoC accredited hospitals.

Original languageEnglish (US)
Pages (from-to)432-442
Number of pages11
JournalJournal of Surgical Research
Volume267
DOIs
StatePublished - Nov 2021

Keywords

  • Colon cancer
  • Geographic disparities
  • Socioeconomic disparities
  • Texas, Mexico

ASJC Scopus subject areas

  • Surgery

Fingerprint

Dive into the research topics of 'Treatment and Survival Disparities of Colon Cancer in the Texas-Mexico Border Population: Cancer Disparities in Border Population'. Together they form a unique fingerprint.

Cite this