Treatment of cutaneous sclerosis and aplastic anemia with antithymocyte globulin

E. P. Balaban, R. G. Sheehan, P. E. Lipsky, E. P. Frenkel

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

We administered antithymocyte globulin to a 52-year-old man with cutaneous sclerosis (scleroderma) and severe aplastic anemia for treatment of the aplastic lesion. The use of this therapy resulted not only in marrow recovery but also in resolution of the sclerosis. This observation indicates that T lymphocytes, their products, or both, are important factors in the pathogenesis of cutaneous sclerosis. Furthermore, the success of this treatment could play a role in future investigations involving the treatment of scleroderma and scleroderma-like conditions.

Original languageEnglish (US)
Pages (from-to)56-58
Number of pages3
JournalAnnals of internal medicine
Volume106
Issue number1
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Internal Medicine

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