Treatment of In-Stent Restenosis Using Excimer Laser Coronary Atherectomy and Bioresorbable Vascular Scaffold Guided by Optical Coherence Tomography

Gabriel Tensol Rodrigues Pereira, Luis Augusto P. Dallan, Armando Vergara-Martel, Mohamad Amer Alaiti, Hiram Grando Bezerra

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The rate of in-stent restenosis (ISR) has become increasingly prevalent with the exponential growth in stent implantation due to an aging population and a higher life expectancy, in addition to the high rates of obesity and diabetes. In this prospective, single operator, all-comer study, we sought to analyze the performance of ELCA followed by bioresorbable vascular scaffold (BVS) placement in patients undergoing percutaneous coronary intervention (PCI) for ISR. A total of 13 patients had ISR treated with a combination of ELCA and BVS, with 9 patients having matched OCT pre, post ELCA and post BVS. Mean age was 65 ± 11.22 and 83% of the patients were male. Hypertension and dyslipidemia were present in 100% of the patients and smoking and diabetes in 50%. After the procedure, we did not detect residual stenosis over 10% in any patient, resulting in a technical success of 100%. No patients had MACE during their hospital stay or within the next six months, resulting in a procedure success of 100%. The mean lumen area increased 0.35 mm2 from pre procedure to post ELCA and 3.58 mm2 from post ELCA to post BVS. The final difference, from pre procedure to post BVS, was a 3.93 mm2 lumen area gain. The mean lumen diameter increased 0.11 mm from baseline to ELCA, 0.95 mm from post laser to BVS implantation and 1.06 mm from pre procedure to post BVS. The NIH area reduced 0.48 mm2 from pre to post ELCA, 1.13mm2 from post ELCA to BVS implantation and 1.61 mm2 from baseline to post BVS implantation. We conclude that ELCA is a safe and feasible debulking method to approach ISR, with high rates of post-procedural BVS success, within six months follow-up.

Original languageEnglish (US)
Pages (from-to)44-49
Number of pages6
JournalCardiovascular Revascularization Medicine
Volume22
DOIs
StatePublished - Jan 2021
Externally publishedYes

Keywords

  • Bioresorbable vascular scaffold (BVS)
  • Complex percutaneous coronary intervention (PCI)
  • Excimer laser coronary atherectomy (ELCA)
  • Optical coherence tomography (OCT)
  • Stent restenosis (ISR)

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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