Treatment of metastatic adrenal cortical carcinoma with cisplatin and etoposide (VP-16)

D. H. Johnson, F. A. Greco

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Two patients with metastatic adrenal cortical carcinoma were treated with cisplatin and etoposide. Both achieved a partial remission after only one cycle. One patient had a 'nonfunctioning' tumor that had previously regressed on mitotane whereas the second patient presented with classical Cushing's syndrome. Although the latter patient's urinary 17-ketosteroids normalized while receiving mitotane, the tumor itself failed to regress objectively. Cisplatin plus etoposide appears to be an active combination for the treatment of metastatic adrenal cortical carcinoma.

Original languageEnglish (US)
Pages (from-to)2198-2202
Number of pages5
JournalCancer
Volume58
Issue number10
StatePublished - 1986

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Adrenocortical Carcinoma
Etoposide
Cisplatin
Mitotane
17-Ketosteroids
Cushing Syndrome
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Treatment of metastatic adrenal cortical carcinoma with cisplatin and etoposide (VP-16). / Johnson, D. H.; Greco, F. A.

In: Cancer, Vol. 58, No. 10, 1986, p. 2198-2202.

Research output: Contribution to journalArticle

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