Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002

Roger Bedimo, Ray Y. Chen, Neil A. Accortt, James L. Raper, Carol Linn, Jeroan J. Allison, John Dubay, Michael S. Saag, Craig J. Hoesley

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Abstract

In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P < .0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P < .0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.

Original languageEnglish (US)
Pages (from-to)1380-1384
Number of pages5
JournalClinical Infectious Diseases
Volume39
Issue number9
DOIs
StatePublished - Nov 1 2004

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ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Bedimo, R., Chen, R. Y., Accortt, N. A., Raper, J. L., Linn, C., Allison, J. J., Dubay, J., Saag, M. S., & Hoesley, C. J. (2004). Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002. Clinical Infectious Diseases, 39(9), 1380-1384. https://doi.org/10.1086/424883