Trends in use of anti-thrombotic agents and outcomes in patients with non-ST-segment elevation myocardial infarction (NSTEMI) managed with an invasive strategy

S. A. Wayangankar, M. T. Roe, A. Y. Chen, R. S. Gupta, R. P. Giugliano, L. K. Newby, James A de Lemos, K. P. Alexander, T. A. Sanborn, J. F. Saucedo

Research output: Contribution to journalArticle

Abstract

Objective: To analyze trends in utilization of anti-thrombotic agents (ATA) and in-hospital clinical outcomes in non-ST-elevation myocardial infarction (NSTEMI) patients managed with an invasive strategy from 2007 to 2010. Methods & results: Using ACTION Registry®-GWTG™ data, we analyzed trends in use of ATA and in-hospital clinical outcomes among 64,199 NSTEMI patients managed invasively between 2007 and 2010. ATA included unfractionated heparin (UFH), low molecular weight heparin (LMWH), glycoprotein IIb/IIIa inhibitors (GPI) and bivalirudin. Although the proportion of NSTEMI patients treated with PCI within 48h of hospital arrival was similar in 2007 and 2010, percentage use of bivalirudin (13.4-27.3%; p

Original languageEnglish (US)
JournalIndian Heart Journal
DOIs
StateAccepted/In press - Aug 3 2015

Keywords

  • Anti-thrombotic agents
  • Invasive strategy
  • Non-ST-segment elevation myocardial infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Wayangankar, S. A., Roe, M. T., Chen, A. Y., Gupta, R. S., Giugliano, R. P., Newby, L. K., de Lemos, J. A., Alexander, K. P., Sanborn, T. A., & Saucedo, J. F. (Accepted/In press). Trends in use of anti-thrombotic agents and outcomes in patients with non-ST-segment elevation myocardial infarction (NSTEMI) managed with an invasive strategy. Indian Heart Journal. https://doi.org/10.1016/j.ihj.2015.09.036