Treponema pallidum pallidum genotypes and macrolide resistance status in syphilitic lesions among patients at 2 sexually transmitted infection clinics in Lima, Peru

Juan Antonio Flores, Silver Keith Vargas, Segundo Ramos Leon, Danny Giancarlo Perez, Lourdes Beatriz Ramos, Jeremy Chow, Kelika Anne Konda, Gino Mauricio Calvo, Hector J. Salvatierra, Jeffrey D. Klaussner, Carlos Fernando Caceres

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru.We implemented and used amolecular typing scheme to describe local T. pallidum pallidum strains. Among 14 specimens, subtype 14d/f was the most prevalent strain in 7 fully typed T. pallidum DNA specimens obtained from men who have sex with men and transgender women presenting with chancre-like lesions. No macrolide-resistance mutations were found in T. pallidum DNA from 10 lesions.

Original languageEnglish (US)
Pages (from-to)465-466
Number of pages2
JournalSexually Transmitted Diseases
Volume43
Issue number7
DOIs
StatePublished - Jun 21 2016

Fingerprint

Treponema pallidum
Peru
Globus Pallidus
Macrolides
Sexually Transmitted Diseases
Chancre
Genotype
Transgender Persons
Reproductive Health
Mutation
DNA
T-DNA

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Treponema pallidum pallidum genotypes and macrolide resistance status in syphilitic lesions among patients at 2 sexually transmitted infection clinics in Lima, Peru. / Flores, Juan Antonio; Vargas, Silver Keith; Leon, Segundo Ramos; Perez, Danny Giancarlo; Ramos, Lourdes Beatriz; Chow, Jeremy; Konda, Kelika Anne; Calvo, Gino Mauricio; Salvatierra, Hector J.; Klaussner, Jeffrey D.; Caceres, Carlos Fernando.

In: Sexually Transmitted Diseases, Vol. 43, No. 7, 21.06.2016, p. 465-466.

Research output: Contribution to journalArticle

Flores, JA, Vargas, SK, Leon, SR, Perez, DG, Ramos, LB, Chow, J, Konda, KA, Calvo, GM, Salvatierra, HJ, Klaussner, JD & Caceres, CF 2016, 'Treponema pallidum pallidum genotypes and macrolide resistance status in syphilitic lesions among patients at 2 sexually transmitted infection clinics in Lima, Peru', Sexually Transmitted Diseases, vol. 43, no. 7, pp. 465-466. https://doi.org/10.1097/OLQ.0000000000000465
Flores, Juan Antonio ; Vargas, Silver Keith ; Leon, Segundo Ramos ; Perez, Danny Giancarlo ; Ramos, Lourdes Beatriz ; Chow, Jeremy ; Konda, Kelika Anne ; Calvo, Gino Mauricio ; Salvatierra, Hector J. ; Klaussner, Jeffrey D. ; Caceres, Carlos Fernando. / Treponema pallidum pallidum genotypes and macrolide resistance status in syphilitic lesions among patients at 2 sexually transmitted infection clinics in Lima, Peru. In: Sexually Transmitted Diseases. 2016 ; Vol. 43, No. 7. pp. 465-466.
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