TY - JOUR
T1 - Treponema pallidum pallidum genotypes and macrolide resistance status in syphilitic lesions among patients at 2 sexually transmitted infection clinics in Lima, Peru
AU - Flores, Juan Antonio
AU - Vargas, Silver Keith
AU - Leon, Segundo Ramos
AU - Perez, Danny Giancarlo
AU - Ramos, Lourdes Beatriz
AU - Chow, Jeremy
AU - Konda, Kelika Anne
AU - Calvo, Gino Mauricio
AU - Salvatierra, Hector J.
AU - Klaussner, Jeffrey D.
AU - Caceres, Carlos Fernando
N1 - Funding Information:
This research was supported by National Institute of Allergy and Infectious Diseases (NIAID: R01AI099727-01).
Publisher Copyright:
Copyright © 2016 American Sexually Transmitted Diseases Association. All rights reserved.
PY - 2016/6/21
Y1 - 2016/6/21
N2 - We report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru.We implemented and used amolecular typing scheme to describe local T. pallidum pallidum strains. Among 14 specimens, subtype 14d/f was the most prevalent strain in 7 fully typed T. pallidum DNA specimens obtained from men who have sex with men and transgender women presenting with chancre-like lesions. No macrolide-resistance mutations were found in T. pallidum DNA from 10 lesions.
AB - We report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru.We implemented and used amolecular typing scheme to describe local T. pallidum pallidum strains. Among 14 specimens, subtype 14d/f was the most prevalent strain in 7 fully typed T. pallidum DNA specimens obtained from men who have sex with men and transgender women presenting with chancre-like lesions. No macrolide-resistance mutations were found in T. pallidum DNA from 10 lesions.
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U2 - 10.1097/OLQ.0000000000000465
DO - 10.1097/OLQ.0000000000000465
M3 - Article
C2 - 27322050
AN - SCOPUS:84975815651
SN - 0148-5717
VL - 43
SP - 465
EP - 466
JO - Sexually Transmitted Diseases
JF - Sexually Transmitted Diseases
IS - 7
ER -