Trichodysplasia spinulosa in a child: Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine

Bahir H. Chamseddin; Bao Anh Patrick D. Tran; Eunice E. Lee; Diana V. Pastrana; Christopher B. Buck; Richard C. Wang; Anna Yasmine Kirkorian

doi:10.1111/pde.13857

Trichodysplasia spinulosa in a child: Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine

Bahir H. Chamseddin, Bao Anh Patrick D. Tran, Eunice E. Lee, Diana V. Pastrana, Christopher B. Buck, Richard C. Wang, Anna Yasmine Kirkorian

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A 6-year-old girl with a history of chronic immunosuppression following small bowel and colon transplantation for tufting enteropathy presented with a diffuse, facial-predominant eruption composed of pink-to-skin-colored papules with central white dystrophic spicules. Histology from a punch biopsy and polymerase chain reaction (PCR) from plucked spicules confirmed a diagnosis of trichodysplasia spinulosa (TS). Additional molecular studies identified several strains of the trichodysplasia spinulosa–associated polyomavirus infecting multiple tissues of the patient, confirming the systemic nature of trichodysplasia spinulosa infections.

Original language	English (US)
Pages (from-to)	723-724
Number of pages	2
Journal	Pediatric dermatology
Volume	36
Issue number	5
DOIs	https://doi.org/10.1111/pde.13857
State	Published - Sep 1 2019

Keywords

diagnosis
pediatric
trichodysplasia spinulosa
trichodysplasia spinulosa–associated polyomavirus

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Dermatology

Access to Document

10.1111/pde.13857

Cite this

@article{1d67ad4cd4e74ad7bc367972f223760b,

title = "Trichodysplasia spinulosa in a child: Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine",

abstract = "A 6-year-old girl with a history of chronic immunosuppression following small bowel and colon transplantation for tufting enteropathy presented with a diffuse, facial-predominant eruption composed of pink-to-skin-colored papules with central white dystrophic spicules. Histology from a punch biopsy and polymerase chain reaction (PCR) from plucked spicules confirmed a diagnosis of trichodysplasia spinulosa (TS). Additional molecular studies identified several strains of the trichodysplasia spinulosa–associated polyomavirus infecting multiple tissues of the patient, confirming the systemic nature of trichodysplasia spinulosa infections.",

keywords = "diagnosis, pediatric, trichodysplasia spinulosa, trichodysplasia spinulosa–associated polyomavirus",

author = "Chamseddin, {Bahir H.} and Tran, {Bao Anh Patrick D.} and Lee, {Eunice E.} and Pastrana, {Diana V.} and Buck, {Christopher B.} and Wang, {Richard C.} and Kirkorian, {Anna Yasmine}",

note = "Publisher Copyright: {\textcopyright} 2019 Wiley Periodicals, Inc.",

year = "2019",

month = sep,

day = "1",

doi = "10.1111/pde.13857",

language = "English (US)",

volume = "36",

pages = "723--724",

journal = "Pediatric dermatology",

issn = "0736-8046",

publisher = "Wiley-Blackwell",

number = "5",

}

TY - JOUR

T1 - Trichodysplasia spinulosa in a child

T2 - Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine

AU - Chamseddin, Bahir H.

AU - Tran, Bao Anh Patrick D.

AU - Lee, Eunice E.

AU - Pastrana, Diana V.

AU - Buck, Christopher B.

AU - Wang, Richard C.

AU - Kirkorian, Anna Yasmine

PY - 2019/9/1

Y1 - 2019/9/1

N2 - A 6-year-old girl with a history of chronic immunosuppression following small bowel and colon transplantation for tufting enteropathy presented with a diffuse, facial-predominant eruption composed of pink-to-skin-colored papules with central white dystrophic spicules. Histology from a punch biopsy and polymerase chain reaction (PCR) from plucked spicules confirmed a diagnosis of trichodysplasia spinulosa (TS). Additional molecular studies identified several strains of the trichodysplasia spinulosa–associated polyomavirus infecting multiple tissues of the patient, confirming the systemic nature of trichodysplasia spinulosa infections.

AB - A 6-year-old girl with a history of chronic immunosuppression following small bowel and colon transplantation for tufting enteropathy presented with a diffuse, facial-predominant eruption composed of pink-to-skin-colored papules with central white dystrophic spicules. Histology from a punch biopsy and polymerase chain reaction (PCR) from plucked spicules confirmed a diagnosis of trichodysplasia spinulosa (TS). Additional molecular studies identified several strains of the trichodysplasia spinulosa–associated polyomavirus infecting multiple tissues of the patient, confirming the systemic nature of trichodysplasia spinulosa infections.

KW - diagnosis

KW - pediatric

KW - trichodysplasia spinulosa

KW - trichodysplasia spinulosa–associated polyomavirus

UR - http://www.scopus.com/inward/record.url?scp=85067417468&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85067417468&partnerID=8YFLogxK

U2 - 10.1111/pde.13857

DO - 10.1111/pde.13857

M3 - Article

C2 - 31190328

AN - SCOPUS:85067417468

SN - 0736-8046

VL - 36

SP - 723

EP - 724

JO - Pediatric dermatology

JF - Pediatric dermatology

IS - 5

ER -

Trichodysplasia spinulosa in a child: Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this