Trichodysplasia spinulosa in a child: Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine

Bahir H. Chamseddin, Bao Anh Patrick D. Tran, Eunice E. Lee, Diana V. Pastrana, Christopher B. Buck, Richard C. Wang, Anna Yasmine Kirkorian

Research output: Contribution to journalArticle

Abstract

A 6-year-old girl with a history of chronic immunosuppression following small bowel and colon transplantation for tufting enteropathy presented with a diffuse, facial-predominant eruption composed of pink-to-skin-colored papules with central white dystrophic spicules. Histology from a punch biopsy and polymerase chain reaction (PCR) from plucked spicules confirmed a diagnosis of trichodysplasia spinulosa (TS). Additional molecular studies identified several strains of the trichodysplasia spinulosa–associated polyomavirus infecting multiple tissues of the patient, confirming the systemic nature of trichodysplasia spinulosa infections.

Original languageEnglish (US)
Pages (from-to)723-724
Number of pages2
JournalPediatric dermatology
Volume36
Issue number5
DOIs
StatePublished - Sep 1 2019

Keywords

  • diagnosis
  • pediatric
  • trichodysplasia spinulosa
  • trichodysplasia spinulosa–associated polyomavirus

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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