Trichodysplasia spinulosa in a child: Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine

Bahir H. Chamseddin, Bao Anh Patrick D. Tran, Eunice E. Lee, Diana V. Pastrana, Christopher B. Buck, Richard C Wang, Anna Yasmine Kirkorian

Research output: Contribution to journalArticle

Abstract

A 6-year-old girl with a history of chronic immunosuppression following small bowel and colon transplantation for tufting enteropathy presented with a diffuse, facial-predominant eruption composed of pink-to-skin-colored papules with central white dystrophic spicules. Histology from a punch biopsy and polymerase chain reaction (PCR) from plucked spicules confirmed a diagnosis of trichodysplasia spinulosa (TS). Additional molecular studies identified several strains of the trichodysplasia spinulosa–associated polyomavirus infecting multiple tissues of the patient, confirming the systemic nature of trichodysplasia spinulosa infections.

Original languageEnglish (US)
JournalPediatric Dermatology
DOIs
StatePublished - Jan 1 2019

Fingerprint

Polyomavirus
Immunosuppression
Histology
Colon
Transplantation
Urine
Biopsy
Polymerase Chain Reaction
Skin
Infection
Serum

Keywords

  • diagnosis
  • pediatric
  • trichodysplasia spinulosa
  • trichodysplasia spinulosa–associated polyomavirus

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

Cite this

Trichodysplasia spinulosa in a child : Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine. / Chamseddin, Bahir H.; Tran, Bao Anh Patrick D.; Lee, Eunice E.; Pastrana, Diana V.; Buck, Christopher B.; Wang, Richard C; Kirkorian, Anna Yasmine.

In: Pediatric Dermatology, 01.01.2019.

Research output: Contribution to journalArticle

Chamseddin, Bahir H. ; Tran, Bao Anh Patrick D. ; Lee, Eunice E. ; Pastrana, Diana V. ; Buck, Christopher B. ; Wang, Richard C ; Kirkorian, Anna Yasmine. / Trichodysplasia spinulosa in a child : Identification of trichodysplasia spinulosa-associated polyomavirus in skin, serum, and urine. In: Pediatric Dermatology. 2019.
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