Trypanosoma brucei γ-glutamylcysteine synthetase. Characterization of the kinetic mechanism and the role of Cys-319 in cystamine inactivation

Medicine & Life Sciences

• Cystamine 100%
• Glutamate-Cysteine Ligase 88%
• Trypanosoma brucei brucei 80%
• Kinetics 44%
• Enzymes 33%
• trypanothione 31%
• Aminobutyrates 25%
• Glutathione 23%
• Catalytic Domain 23%
• Adenosine Triphosphate 13%
• Spermidine 11%
• Catalysis 10%
• Oxidation-Reduction 8%
• Mutation 4%

Chemical Compounds

• Cystamine 87%
• Trypanothione 38%
• Glutathione 33%
• Kd 18%
• Spermidine 15%
• Parasitic 15%
• Label 10%
• Mutation 10%
• Biosynthesis 10%
• Catalysis 7%