Tuberous sclerosis

E. S. Roach, M. R. Delgado

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Tuberous sclerosis complex is a disorder of cellular differentiation and proliferation that is inherited as an autosomal dominant trait with variable penetrance and a high spontaneous mutation rate. Lesions occur in the brain, skin, kidneys, heart, and other organs. Recent studies suggest genetic heterogeneity, with at least two gene loci on chromosomes 9, 16, and perhaps 11.

Original languageEnglish (US)
Pages (from-to)151-161
Number of pages11
JournalDermatologic Clinics
Volume13
Issue number1
StatePublished - 1995

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Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 9
Tuberous Sclerosis
Genetic Heterogeneity
Penetrance
Mutation Rate
Cell Proliferation
Kidney
Skin
Brain
Genes

ASJC Scopus subject areas

  • Dermatology

Cite this

Roach, E. S., & Delgado, M. R. (1995). Tuberous sclerosis. Dermatologic Clinics, 13(1), 151-161.

Tuberous sclerosis. / Roach, E. S.; Delgado, M. R.

In: Dermatologic Clinics, Vol. 13, No. 1, 1995, p. 151-161.

Research output: Contribution to journalArticle

Roach, ES & Delgado, MR 1995, 'Tuberous sclerosis', Dermatologic Clinics, vol. 13, no. 1, pp. 151-161.
Roach, E. S. ; Delgado, M. R. / Tuberous sclerosis. In: Dermatologic Clinics. 1995 ; Vol. 13, No. 1. pp. 151-161.
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