Tuberous sclerosis complex.

S. P. Sparagana, E. S. Roach

Research output: Contribution to journalReview article

108 Scopus citations

Abstract

Tuberous sclerosis complex is an autosomal dominant disorder that causes significant complications in multiple organ systems. Both basic science and clinical research on tuberous sclerosis complex have flourished in recent years, improving our understanding of its molecular genetics and pathophysiology. Two tuberous sclerosis complex genes cause nearly identical phenotypes, and great progress has been made towards understanding how each of these genes functions. The recognition of tuberous sclerosis complex improved with revised diagnostic criteria, and the management of many of the complications of tuberous sclerosis complex has improved.

Original languageEnglish (US)
Pages (from-to)115-119
Number of pages5
JournalCurrent opinion in neurology
Volume13
Issue number2
DOIs
StatePublished - Apr 2000

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ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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