Tuberous sclerosis complex.

S. P. Sparagana, E. S. Roach

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

Tuberous sclerosis complex is an autosomal dominant disorder that causes significant complications in multiple organ systems. Both basic science and clinical research on tuberous sclerosis complex have flourished in recent years, improving our understanding of its molecular genetics and pathophysiology. Two tuberous sclerosis complex genes cause nearly identical phenotypes, and great progress has been made towards understanding how each of these genes functions. The recognition of tuberous sclerosis complex improved with revised diagnostic criteria, and the management of many of the complications of tuberous sclerosis complex has improved.

Original languageEnglish (US)
Pages (from-to)115-119
Number of pages5
JournalCurrent Opinion in Neurology
Volume13
Issue number2
StatePublished - Apr 2000

Fingerprint

Tuberous Sclerosis
Genes
Molecular Biology
Phenotype
Research

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Tuberous sclerosis complex. / Sparagana, S. P.; Roach, E. S.

In: Current Opinion in Neurology, Vol. 13, No. 2, 04.2000, p. 115-119.

Research output: Contribution to journalArticle

Sparagana, SP & Roach, ES 2000, 'Tuberous sclerosis complex.', Current Opinion in Neurology, vol. 13, no. 2, pp. 115-119.
Sparagana, S. P. ; Roach, E. S. / Tuberous sclerosis complex. In: Current Opinion in Neurology. 2000 ; Vol. 13, No. 2. pp. 115-119.
@article{81c8bc64113945a59532c522fc241e0c,
title = "Tuberous sclerosis complex.",
abstract = "Tuberous sclerosis complex is an autosomal dominant disorder that causes significant complications in multiple organ systems. Both basic science and clinical research on tuberous sclerosis complex have flourished in recent years, improving our understanding of its molecular genetics and pathophysiology. Two tuberous sclerosis complex genes cause nearly identical phenotypes, and great progress has been made towards understanding how each of these genes functions. The recognition of tuberous sclerosis complex improved with revised diagnostic criteria, and the management of many of the complications of tuberous sclerosis complex has improved.",
author = "Sparagana, {S. P.} and Roach, {E. S.}",
year = "2000",
month = "4",
language = "English (US)",
volume = "13",
pages = "115--119",
journal = "Current Opinion in Neurology",
issn = "1350-7540",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Tuberous sclerosis complex.

AU - Sparagana, S. P.

AU - Roach, E. S.

PY - 2000/4

Y1 - 2000/4

N2 - Tuberous sclerosis complex is an autosomal dominant disorder that causes significant complications in multiple organ systems. Both basic science and clinical research on tuberous sclerosis complex have flourished in recent years, improving our understanding of its molecular genetics and pathophysiology. Two tuberous sclerosis complex genes cause nearly identical phenotypes, and great progress has been made towards understanding how each of these genes functions. The recognition of tuberous sclerosis complex improved with revised diagnostic criteria, and the management of many of the complications of tuberous sclerosis complex has improved.

AB - Tuberous sclerosis complex is an autosomal dominant disorder that causes significant complications in multiple organ systems. Both basic science and clinical research on tuberous sclerosis complex have flourished in recent years, improving our understanding of its molecular genetics and pathophysiology. Two tuberous sclerosis complex genes cause nearly identical phenotypes, and great progress has been made towards understanding how each of these genes functions. The recognition of tuberous sclerosis complex improved with revised diagnostic criteria, and the management of many of the complications of tuberous sclerosis complex has improved.

UR - http://www.scopus.com/inward/record.url?scp=0034166557&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034166557&partnerID=8YFLogxK

M3 - Article

C2 - 10987566

AN - SCOPUS:0034166557

VL - 13

SP - 115

EP - 119

JO - Current Opinion in Neurology

JF - Current Opinion in Neurology

SN - 1350-7540

IS - 2

ER -