Abstract
MicroRNAs (miRNAs) and the pathways that regulate their expression have critical functions during normal development. A new study demonstrates that select cancer cells have appropriated one developmental mechanism of miRNA regulation, the inhibition of let-7 biogenesis by the Lin-28 and Lin-28B RNA binding proteins, to rid themselves of an antitumorigenic miRNA.
Original language | English (US) |
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Pages (from-to) | 768-769 |
Number of pages | 2 |
Journal | Nature genetics |
Volume | 41 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2009 |
ASJC Scopus subject areas
- Genetics