Abstract
Alcohols were replaced by a two-carbon nitrile unit in good to excellent yields via dehydrative alkylation with (phenylsulfonyl)acetonitrile under modified Mitsunobu conditions followed by desulfonylation using magnesium. Diols and haloalcohols furnished cycloalkylnitriles.
Original language | English (US) |
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Pages (from-to) | 5691-5694 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 36 |
Issue number | 32 |
DOIs | |
State | Published - Aug 7 1995 |
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery