TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION

Eric J. Weinlander; Angeline L. Wang; Pimkwan Jaru-Ampornpan; Michael M. Altaweel; T. Michael Nork

doi:10.1097/ICB.0000000000000567

TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION

Eric J. Weinlander, Angeline L. Wang, Pimkwan Jaru-Ampornpan, Michael M. Altaweel, T. Michael Nork

Research output: Contribution to journal › Article

Abstract

Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.

Original language	English (US)
Pages (from-to)	241-243
Number of pages	3
Journal	Retinal Cases and Brief Reports
Volume	13
Issue number	3
DOIs	https://doi.org/10.1097/ICB.0000000000000567
State	Published - Jun 1 2019
Externally published	Yes

Keywords

acute retinal necrosis
prior shingles vaccination
varicella zoster virus

ASJC Scopus subject areas

Ophthalmology

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10.1097/ICB.0000000000000567

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Weinlander, E. J., Wang, A. L., Jaru-Ampornpan, P., Altaweel, M. M., & Nork, T. M. (2019). TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION. Retinal Cases and Brief Reports, 13(3), 241-243. https://doi.org/10.1097/ICB.0000000000000567

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abstract = "Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.",

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author = "Weinlander, {Eric J.} and Wang, {Angeline L.} and Pimkwan Jaru-Ampornpan and Altaweel, {Michael M.} and Nork, {T. Michael}",

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AU - Weinlander, Eric J.

AU - Wang, Angeline L.

AU - Jaru-Ampornpan, Pimkwan

AU - Altaweel, Michael M.

AU - Nork, T. Michael

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AB - Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.

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