TY - JOUR
T1 - TWO CASES of ACUTE RETINAL NECROSIS DUE to VARICELLA ZOSTER DESPITE PRIOR SHINGLES VACCINATION
AU - Weinlander, Eric J.
AU - Wang, Angeline L.
AU - Jaru-Ampornpan, Pimkwan
AU - Altaweel, Michael M.
AU - Nork, T. Michael
N1 - Funding Information:
Supported by Research to Prevent Blindness, National Institutes of Health (NIH) P30 EY016665, and McPherson Eye Research Institute’s Retina Research Foundation Kathryn & Latimer Murfee Chair. None of the authors has any conflicting interests to disclose.
Publisher Copyright:
Copyright © by Ophthalmic Communications Society, Inc. Unauthorized reproduction of this article is prohibited.
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.
AB - Purpose:To review two cases of acute retinal necrosis in adults due to varicella zoster virus despite prior shingles vaccination.Methods:Retrospective chart review.Patients:A 62-year-old man and a 64-year-old man with unilateral acute retinal necrosis who had shingles vaccinations 16 and 7 months before their ocular symptoms.Results:Polymerase chain reaction confirmation of varicella zoster virus in the anterior chambers of both patients. Both patients had good responses to oral antiviral therapy and topical and/or oral steroids.Discussion:These two cases demonstrate that singles vaccination is not an absolute protection against varicella zoster virus-related acute retinal necrosis. However, such vaccination may reduce the severity of the acute retinal necrosis.
KW - acute retinal necrosis
KW - prior shingles vaccination
KW - varicella zoster virus
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U2 - 10.1097/ICB.0000000000000567
DO - 10.1097/ICB.0000000000000567
M3 - Article
C2 - 28291069
AN - SCOPUS:85066404174
VL - 13
SP - 241
EP - 243
JO - Retinal Cases and Brief Reports
JF - Retinal Cases and Brief Reports
SN - 1935-1089
IS - 3
ER -