To improve adherence to dietary sodium restriction, we validated two simple techniques for providing rapid and accurate estimates of urinary content - overnight urine collections and an immediate analysis of urine sodium content. These techniques were then applied in a trial with a group of patients with hypertension who were considered to be resistant to the adoption of dietary changes. After six months, 68% of the patients on the lower-sodium diet reduced their urine sodium content by one third or more. They had an 11-mg Hg fall in mean BP compared with a 3-mm Hg rise in the control group, who were not on a lower-sodium diet, and a lesser fall in plasma potassium levels.
ASJC Scopus subject areas
- Internal Medicine