Two-Year Results of the Prospective Spine Treatment Outcomes Study: Analysis of Postoperative Clinical Outcomes Between Patients with and without a History of Previous Cervical Spine Surgery

Kris Radcliff, Cyrus Jalai, Shaleen Vira, Sun Yang, Anthony J. Boniello, Kristina Bianco, Cheongeun Oh, Michael Gerling, Gregory Poorman, Samantha R. Horn, John A. Buza, Robert E. Isaacs, Alexander R. Vaccaro, Peter G. Passias

Research output: Contribution to journalArticle

2 Scopus citations


Objective History of previous cervical spine surgery is a frequently cited cause of worse outcomes after cervical spine surgery. The purpose of this study was to determine any differences in clinical outcomes after cervical spine surgery between patients with and without a history of previous cervical spine surgery. Methods A multicenter prospective database was reviewed retrospectively to identify patients with cervical spondylosis undergoing surgery with a minimum 2-year follow-up. Patients were divided into 2 groups: patients with (W) or without (WO) previous history of cervical spine surgery. Statistical analyses of Health-Related Quality of Life scores were analyzed with statistical software to fit linear mixed models for continuous longitudinal outcome. Results A total of 1286 patients (377 W, 909 WO) met criteria for inclusion. Overall, patients in both groups experienced an improvement in their Health-Related Quality of Life scores. However, patients in the W group had significantly decreased improvement compared with WO patients in the Neck Disability Index score and the following SF-36 domain scores: Role Physical, Bodily Pain, General Health, Vitality, Social Functioning, Health Transition, and Physical Component Summary at all time points (P < 0.05). There was no statistically significant difference between the W and WO groups in operative time, estimated blood loss, length of stay, or complications (P > 0.05). Conclusions Patients with a history of previous cervical spine surgery had inferior improvement in quality of life outcome scores. Patients with a history of previous surgical intervention who elect to undergo subsequent surgeries should be appropriately counseled about expected results.

Original languageEnglish (US)
Pages (from-to)e144-e149
JournalWorld Neurosurgery
Publication statusPublished - Jan 2018
Externally publishedYes



  • Cervical
  • Cervical spine surgery
  • Cervical spondylotic myelopathy
  • History
  • Revision surgery
  • Spondylosis

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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