Type 2 diabetes and uric acid nephrolithiasis

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Type 2 diabetes is associated with an increased propensity for uric acid nephrolithiasis. In individuals with diabetes, this increased risk is due to a lower urine pH that results from obesity, dietary factors, and impaired renal ammoniagenesis. The epidemiology and pathogenesis of uric acid stone disease in patients with diabetes are hereby reviewed, and potential molecular mechanisms are proposed.

Original languageEnglish (US)
Title of host publicationRenal Stone Disease 2 - 2nd International Urolithiasis Research Symposium
Number of pages5
StatePublished - Oct 22 2008
Event2nd International Urolithiasis Research Symposium - Indianapolis, IN, United States
Duration: Apr 17 2008Apr 18 2008

Publication series

NameAIP Conference Proceedings
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616


Other2nd International Urolithiasis Research Symposium
CountryUnited States
CityIndianapolis, IN



  • Nephrolithiasis
  • Type 2 diabetes
  • Uric acid
  • Urine pH

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Maalouf, N. M. (2008). Type 2 diabetes and uric acid nephrolithiasis. In Renal Stone Disease 2 - 2nd International Urolithiasis Research Symposium (pp. 194-198). (AIP Conference Proceedings; Vol. 1049). https://doi.org/10.1063/1.2998021